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Vol 4, No 2 (2018)
Review paper
Published online: 2018-08-17
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The role of oxidative-antioxidative balance in etiopathogenesis of vitiligo
1, , , , , ,
Forum Dermatologicum 2018;4(2):63-69.
Affiliations- Klinika Dermatologii, Chorób Przenoszonych Drogą Płciową i Immunodermatologii, ul. Curie-Skłodowskiej 9, 85-094 Bydgoszcz, Poland
open access
Vol 4, No 2 (2018)
REVIEW ARTICLES
Published online: 2018-08-17
Abstract
Oxidative stress plays an important role in the etiopathogenesis of acquired vitiligo. In patients with this disorder, impaied performance of the antioxidant system leads to the accumulation of reactive oxygen species in their skin. Under physiological conditions, they play the role of mediators and regulators of many cellular processes. Their excess, however, leads to the destruction of structural and functional elements of dye cells. Previous studies clearly indicate the share of free radicals in the progression of lesions. The use of antioxidant defense elements, including antioxidants, may prove to be an important element of effective therapy of this disease.
Abstract
Oxidative stress plays an important role in the etiopathogenesis of acquired vitiligo. In patients with this disorder, impaied performance of the antioxidant system leads to the accumulation of reactive oxygen species in their skin. Under physiological conditions, they play the role of mediators and regulators of many cellular processes. Their excess, however, leads to the destruction of structural and functional elements of dye cells. Previous studies clearly indicate the share of free radicals in the progression of lesions. The use of antioxidant defense elements, including antioxidants, may prove to be an important element of effective therapy of this disease.
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Keywords
oxidative stress, oxidative-antioxidative balance, oxygen free radicals, acquired vitiligo, etiology of vitiligo
About this articleTitle
The role of oxidative-antioxidative balance in etiopathogenesis of vitiligo
Journal
Issue
Article type
Review paper
Pages
63-69
Published online
2018-08-17
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Bibliographic record
Forum Dermatologicum 2018;4(2):63-69.
Keywords
oxidative stress
oxidative-antioxidative balance
oxygen free radicals
acquired vitiligo
etiology of vitiligo
Authors
Laura Nowowiejska
Anna Niezgoda
Aleksandra Grzanka
Rafał Czajkowski
Czanita Cieścińska
Alina Woźniak
Karolina Szewczyk-Golec
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