open access

Vol 3, No 3 (2017)
Case report
Published online: 2017-10-24
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Massive cutaneous metastases as a first symptom of breast cancer — a case study

Agnieszka Białecka1, Kaja Męcińska-Jundziłł1, Urszula Adamska1, Anna Kasperska2, Rafał Czajkowski1
Forum Dermatologicum 2017;3(3):75-78.
Affiliations
  1. Nicolaus Copernicus University in Toruń, Faculty of Medicine, Chair of Dermatology, Sexually Transmitted Diseases and Immunodermatology, Skłodowskiej-Curie 9, 85-094 Bydgoszcz, Poland
  2. Nicolaus Copernicus University in Toruń, Faculty of Medicine, Department of Clinical Pathomorphology, Skłodowskiej-Curie 9, 85-094 Bydgoszcz, Poland

open access

Vol 3, No 3 (2017)
CASE STUDY
Published online: 2017-10-24

Abstract

Introduction: Metastases to the skin are relatively rare, but they are an important diagnostic and therapeutic challenge. In women skin metastases are the most commonly associated with breast cancer. In the men they are often associated with lung cancer. Skin metastasis most often are in form of blue-purple nodules and tumours with tendency of necrosis.

Aim: The aim of this paper is to present the case of a patient with diagnosed breast cancer with skin involvement.

Case report: The 48-years old female patient was admitted to The Department of Dermatology for diagnosis and treatment of dermal lesions in form of numerous blue-purple nodules and ulcerations localised on the skin of the chest. The ultrasound examination suggested a primary malignant lesion in the left breast spreading to the right side and numerous satellite nodules. A whole nodule was collected for histopathological and immunohistochemical examinations in order to make the final diagnosis. Histopathology tests confirmed the diagnosis of tumour metastases of the skin and positive immunohistochemical reactions for cytokeratin 7 (CK7) and for oestrogen receptors (ER) pointed mammary glands as the primary site. The patient was urgently referred to the Oncology Centre.

Conclusions: The occurrence of skin metastasis in all tumour processes significantly worsens the prognosis of the patient. These changes should be quickly recognized by the oncologist or dermatologist. Sometimes the localization of primary tumour is not possible to determine without taking the biopsy for histopathological and immunohistochemistry assays. Rapid treatment of appropriate chemotherapy or radiotherapy can prolong life and reduce pain.

Abstract

Introduction: Metastases to the skin are relatively rare, but they are an important diagnostic and therapeutic challenge. In women skin metastases are the most commonly associated with breast cancer. In the men they are often associated with lung cancer. Skin metastasis most often are in form of blue-purple nodules and tumours with tendency of necrosis.

Aim: The aim of this paper is to present the case of a patient with diagnosed breast cancer with skin involvement.

Case report: The 48-years old female patient was admitted to The Department of Dermatology for diagnosis and treatment of dermal lesions in form of numerous blue-purple nodules and ulcerations localised on the skin of the chest. The ultrasound examination suggested a primary malignant lesion in the left breast spreading to the right side and numerous satellite nodules. A whole nodule was collected for histopathological and immunohistochemical examinations in order to make the final diagnosis. Histopathology tests confirmed the diagnosis of tumour metastases of the skin and positive immunohistochemical reactions for cytokeratin 7 (CK7) and for oestrogen receptors (ER) pointed mammary glands as the primary site. The patient was urgently referred to the Oncology Centre.

Conclusions: The occurrence of skin metastasis in all tumour processes significantly worsens the prognosis of the patient. These changes should be quickly recognized by the oncologist or dermatologist. Sometimes the localization of primary tumour is not possible to determine without taking the biopsy for histopathological and immunohistochemistry assays. Rapid treatment of appropriate chemotherapy or radiotherapy can prolong life and reduce pain.

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Keywords

skin metastases, breast cancer, satellite nodules

About this article
Title

Massive cutaneous metastases as a first symptom of breast cancer — a case study

Journal

Forum Dermatologicum

Issue

Vol 3, No 3 (2017)

Article type

Case report

Pages

75-78

Published online

2017-10-24

Page views

8993

Article views/downloads

1105

Bibliographic record

Forum Dermatologicum 2017;3(3):75-78.

Keywords

skin metastases
breast cancer
satellite nodules

Authors

Agnieszka Białecka
Kaja Męcińska-Jundziłł
Urszula Adamska
Anna Kasperska
Rafał Czajkowski

References (12)
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