open access

Vol 3, No 2 (2017)
Review paper
Published online: 2017-08-21
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Topical antibiotics in the treatment of acne

Julia Seniuta1, Adam Reich1
Forum Dermatologicum 2017;3(2):49-52.
Affiliations
  1. Katedra i Klinika Dermatologii, Wenerologii i Alergologii UM, Chałubińskiego 1, 50-368 Wrocław

open access

Vol 3, No 2 (2017)
REVIEW ARTICLES
Published online: 2017-08-21

Abstract

Acne vulgaris is one of the most common reason of dermatological consultation. Pathogenesis of acne is multifactorial, including hormonal disturbances, genetic factors, changes in sebum composition, and colonization of hair follicles with Propionibacterium acnes. About 80% of acne cases have a mild course, which should be treated with topical therapy and proper skin care. Topical anti-acne drugs include antibiotics, retinoids, benzoyl peroxide, and azelaic acid. Antibiotics have antimicrobial and anti-inflammatory properties. They inhibit chemotaxis of neutrophils, cytokine synthesis and macrophage functioning as well as they decrease the number of P. acnes in pilosebaceus units. In contrast to other topical treatment options, topical antibiotics do not cause skin irritation. They can also be safely used in pregnant women as well in children and adolescents.

Abstract

Acne vulgaris is one of the most common reason of dermatological consultation. Pathogenesis of acne is multifactorial, including hormonal disturbances, genetic factors, changes in sebum composition, and colonization of hair follicles with Propionibacterium acnes. About 80% of acne cases have a mild course, which should be treated with topical therapy and proper skin care. Topical anti-acne drugs include antibiotics, retinoids, benzoyl peroxide, and azelaic acid. Antibiotics have antimicrobial and anti-inflammatory properties. They inhibit chemotaxis of neutrophils, cytokine synthesis and macrophage functioning as well as they decrease the number of P. acnes in pilosebaceus units. In contrast to other topical treatment options, topical antibiotics do not cause skin irritation. They can also be safely used in pregnant women as well in children and adolescents.

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Keywords

erythromycin, clindamycin, treatment, Prionibacterium acnes

About this article
Title

Topical antibiotics in the treatment of acne

Journal

Forum Dermatologicum

Issue

Vol 3, No 2 (2017)

Article type

Review paper

Pages

49-52

Published online

2017-08-21

Page views

2186

Article views/downloads

99582

Bibliographic record

Forum Dermatologicum 2017;3(2):49-52.

Keywords

erythromycin
clindamycin
treatment
Prionibacterium acnes

Authors

Julia Seniuta
Adam Reich

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