open access
Calcium dobesilate – new indications
open access
Abstract
Calcium dobesilate is a calcium salt of dobesilic acid which acts selectively on the capillary walls. It seems that calcium dobesilate may be effective in the treatment of diseases with vascular abnormalities. Recently, new data has been published showing significant clinical improvement in various dermatoses, namely pigmented palpable purpura, psoriasis, rosacea, actinic keratosis or even non-melanoma skin cancers. However, it should be underlined, that these reports are based on description of single subjects or small patient groups. Therefore, these observations should be confirmed by other researchers, preferably, in comparative, placebo-controlled studies to support the therapeutic activity of calcium dobesilate.
Abstract
Calcium dobesilate is a calcium salt of dobesilic acid which acts selectively on the capillary walls. It seems that calcium dobesilate may be effective in the treatment of diseases with vascular abnormalities. Recently, new data has been published showing significant clinical improvement in various dermatoses, namely pigmented palpable purpura, psoriasis, rosacea, actinic keratosis or even non-melanoma skin cancers. However, it should be underlined, that these reports are based on description of single subjects or small patient groups. Therefore, these observations should be confirmed by other researchers, preferably, in comparative, placebo-controlled studies to support the therapeutic activity of calcium dobesilate.
Keywords
dobesilate; psoriasis; rosacea; non-melanoma skin cancers; actinic keratosis
About this articleTitle
Calcium dobesilate – new indications
Journal
Issue
Article type
Review paper
Pages
134-138
Published online
2017-02-14
Page views
961
Article views/downloads
11167
Bibliographic record
Forum Dermatologicum 2016;2(4):134-138.
Keywords
dobesilate
psoriasis
rosacea
non-melanoma skin cancers
actinic keratosis
Authors
Karolina Lesner
Adam Reich
