open access
Kyrle’s disease
open access
Abstract
Kyrle’s disease is an acquired perforating dermatosis, which presents as hyperkeratotic papules mainly on the calves, but also on the upper extremities and the trunk. Most commonly it is associated with diabetes mellitus or renal failure, but it exist also without any metabolic disorders. Kyrle’s disease is characterized by the transepithelial elimination of certain dermal material, this feature being common to all acquired perforating disorders. Various therapies have been reported — including keratolytics (salicylic acid and urea), topical and oral retinoids, followed by psoralen plus Ultraviolet A radiation and laserotherapy.
Abstract
Kyrle’s disease is an acquired perforating dermatosis, which presents as hyperkeratotic papules mainly on the calves, but also on the upper extremities and the trunk. Most commonly it is associated with diabetes mellitus or renal failure, but it exist also without any metabolic disorders. Kyrle’s disease is characterized by the transepithelial elimination of certain dermal material, this feature being common to all acquired perforating disorders. Various therapies have been reported — including keratolytics (salicylic acid and urea), topical and oral retinoids, followed by psoralen plus Ultraviolet A radiation and laserotherapy.
Keywords
Kyrle disease; perforating dermatosis; diabetes; renal failure
About this articleTitle
Kyrle’s disease
Journal
Issue
Article type
Review paper
Pages
131-133
Published online
2017-02-14
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1039
Article views/downloads
6287
Bibliographic record
Forum Dermatologicum 2016;2(4):131-133.
Keywords
Kyrle disease
perforating dermatosis
diabetes
renal failure
Authors
Katarzyna Maria Płużańska-Srebrzyńska
Zofia Gerlicz-Kowalczuk
Agnieszka Wojciechowska
Andrzej Kaszuba
