Vol 7, No 4 (2021)
Case report
Published online: 2022-01-31

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Acanthosis nigricans: usefulness of dermoscopy in differential diagnosis

Dominika Kwiatkowska1, Adam Reich1
Forum Dermatologicum 2021;7(4):113-115.

Abstract

Acanthosis nigricans is a skin disease characterized by hyperpigmented plaques, typically located in axillae, groins, inframammary region, neck, and flexor surface of the skin. Numerous systemic disorders may lead to the development of acanthosis nigricans. Here a case of a patient with acanthosis nigricans and tissue resistance to insulin is presented. Moreover, the usefulness of dermoscopy as an additional tool that can help to establish a proper diagnosis is discussed.

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References

  1. Araújo LMB, Porto MV, Netto EM, et al. Association of acanthosis nigricans with race and metabolic disturbances in obese women. Braz J Med Biol Res. 2002; 35(1): 59–64.
  2. Hirt PA, Castillo DE, Yosipovitch G, et al. Skin changes in the obese patient. J Am Acad Dermatol. 2019; 81(5): 1037–1057.
  3. Litonjua P, Piñero-Piloña A, Aviles-Santa L, et al. Prevalence of acanthosis nigricans in newly-diagnosed type 2 diabetes. Endocr Pract. 2004; 10(2): 101–106.
  4. Mendes AL, Miot HA, Haddad V. Diabetes mellitus and the skin. An Bras Dermatol. 2017; 92(1): 8–20.
  5. Stuart CA, Gilkison CR, Keenan BS, et al. Hyperinsulinemia and acanthosis nigricans in African Americans. J Natl Med Assoc. 1997; 89(8): 523–527.
  6. Wedge CC, Rootman DS, Hunter W, et al. Malignant acanthosis nigricans. A case report. Ophthalmology. 1993; 100(10): 1590–1592.
  7. Pardeshi SS, Khemani UN, Kamath RR, et al. Therapeutic implications of dermoscopic findings in acanthosis nigricans: A clinical and histopathological study. Dermatol Ther. 2020; 33(6): e14521.
  8. Elmas ÖF, Demirbaş A, Kutlu Ö, et al. Utility of dermatoscopy in the diagnosis of acanthosis nigricans. J Cosmet Dermatol. 2020; 19(12): 3426–3427.
  9. Krueger L, Saizan A, Stein JA, et al. Dermoscopy of acquired pigmentary disorders: a comprehensive review. Int J Dermatol. 2022; 61(1): 7–19.
  10. Patel NU, Roach C, Alinia H, et al. Current treatment options for acanthosis nigricans. Clin Cosmet Investig Dermatol. 2018; 11: 407–413.
  11. Kapoor S. Diagnosis and treatment of Acanthosis nigricans. Skinmed. 2010; 8(3): 161–4; quiz 165.
  12. Badr D, Kurban M, Abbas O. Metformin in dermatology: an overview. J Eur Acad Dermatol Venereol. 2013; 27(11): 1329–1335.
  13. Higgins SP, Freemark M, Prose NS. Acanthosis nigricans: a practical approach to evaluation and management. Dermatol Online J. 2008; 14(9): 2.
  14. Ozdemir M, Toy H, Mevlitoğlu I, et al. Generalized idiopathic acanthosis nigricans treated with acitretin. J Dermatolog Treat. 2006; 17(1): 54–56.
  15. Walling HW, Messingham M, Myers LM, et al. Improvement of acanthosis nigricans on isotretinoin and metformin. J Drugs Dermatol. 2003; 2(6): 677–681.