Vol 6, No 4 (2020)
Review paper
Published online: 2020-12-08
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The new European League Against Rheumatism/American College of Rheumatology 2019 classification criteria for systemic lupus erythematosus

Izabela Machlarz1, Adam Reich1
Forum Dermatologicum 2020;6(4):108-112.

Abstract

The systemic lupus erythematosus (SLE) is an autoimmune disease which can affect almost all organs. The diagnosis of lupus is hindered by the multitude of similar clinical symptoms occurring at different time intervals, non-specific laboratory abnormalities and histopathological features that may also occur in other diseases. The presence of antibodies against self-antigens, especially antinuclear antibodies, is of great importance in the diagnostic process. Rapid diagnosis of the disease and implementation of appropriate treatment is crucial for therapeutic success and enables to prevent many complications. In 2018, new classification criteria for SLE were developed, namely EULAR/ACR 2019 criteria, which were based on the previous SLICC and ACR criteria but have been markedly modified. These criteria were divided into 7 clinical and 3 immunological domains. The preliminary criterion is at least a single confirmation of the presence of antinuclear antibodies with a titer of ≥ 1: 80, and next to achieving ≥ 10 points from pre-defined symptoms, including at least 1 criterion from the clinical domain. Only one symptom with the highest score from each domain is used for the total sum calculation.

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