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Volumetric analysis of the cranial and nasal cavity from micro-computed tomography scans in the rabbit
, 1, 1, 2, 1
Affiliations- Department of Anatomy, Faculty of Veterinary Medicine, Ankara University, Ziraat District, Şehit Ömer Halisdemir Blvd, Altindag, 06110 Ankara, Türkiye
- Department of Nuclear Medicine, School of Medicine, Ankara University, Cebeci Hospital,, Cebeci Hospital, 06590 Ankara, Türkiye
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Abstract
Background: The aim of the study was to estimate the volume values of the cranial cavity and nasal cavity structures and to compare the efficiency of manual segmentation of three-dimensional reconstruction and Cavalieri’s principle (CP) methodologies.
Materials and methods: Volume values of the cranial cavity, maxillary sinus (MS), dorsal conchal sinus (DCS), dorsal nasal meatus (DNM), middle nasal meatus (MNM), ventral nasal meatus (VNM), ventral nasal concha (VNC), middle nasal concha (MNC) and nasal vestibule (NV) were estimated with manual segmentation and CP from micro-computed tomography images in 5 male New Zealand white rabbits. Volume measurements and elapsed time were compared with each other. Three-dimensional reconstruction models of nasal and cranial cavity structures were created.
Results: There was a statistically significant difference between methods of the MS, DCS, DNM, MNM, VNM, VNC, and MNC volume measurements. Additionally, there was a statistically significant difference between the volumetric analysis time period of the methods and CP was found much shorter than manual segmentation.
Conclusions: Realistic results were achieved in a short time with the CP among the stereology methods. It is thought that these image and quantitative data results can be used for modelling, toxicology and pathology studies such as acute and chronić rhinitis or rhino sinusitis as well as a good understanding of the relationship of the anatomical structures in the nasal cavity.
Abstract
Background: The aim of the study was to estimate the volume values of the cranial cavity and nasal cavity structures and to compare the efficiency of manual segmentation of three-dimensional reconstruction and Cavalieri’s principle (CP) methodologies.
Materials and methods: Volume values of the cranial cavity, maxillary sinus (MS), dorsal conchal sinus (DCS), dorsal nasal meatus (DNM), middle nasal meatus (MNM), ventral nasal meatus (VNM), ventral nasal concha (VNC), middle nasal concha (MNC) and nasal vestibule (NV) were estimated with manual segmentation and CP from micro-computed tomography images in 5 male New Zealand white rabbits. Volume measurements and elapsed time were compared with each other. Three-dimensional reconstruction models of nasal and cranial cavity structures were created.
Results: There was a statistically significant difference between methods of the MS, DCS, DNM, MNM, VNM, VNC, and MNC volume measurements. Additionally, there was a statistically significant difference between the volumetric analysis time period of the methods and CP was found much shorter than manual segmentation.
Conclusions: Realistic results were achieved in a short time with the CP among the stereology methods. It is thought that these image and quantitative data results can be used for modelling, toxicology and pathology studies such as acute and chronić rhinitis or rhino sinusitis as well as a good understanding of the relationship of the anatomical structures in the nasal cavity.
Keywords
Cavalieri’s principle, volume analysis, micro-computed tomography, New Zealand white rabbit, paranasal sinus, concha, meatus
About this articleTitle
Volumetric analysis of the cranial and nasal cavity from micro-computed tomography scans in the rabbit
Journal
Issue
Article type
Original article
Pages
333-338
Published online
2019-07-02
Page views
1954
Article views/downloads
750
DOI
Pubmed
Bibliographic record
Folia Morphol 2020;79(2):333-338.
Keywords
Cavalieri’s principle
volume analysis
micro-computed tomography
New Zealand white rabbit
paranasal sinus
concha
meatus
Authors
C. Bakıcı
R. O. Akgun
O. Ekım
C. Soydal
C. Oto
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