open access

Vol 79, No 3 (2020)
ORIGINAL ARTICLES
Published online: 2019-10-09
Submitted: 2019-08-17
Accepted: 2019-09-27
Get Citation

A plea for extension of the official nomenclature of the microscopic structure of human tissues and organs, the Terminologia Histologica

I. Varga, D. Kachlík, M. Klein
DOI: 10.5603/FM.a2019.0110
·
Pubmed: 31617576
·
Folia Morphol 2020;79(3):610-620.

open access

Vol 79, No 3 (2020)
ORIGINAL ARTICLES
Published online: 2019-10-09
Submitted: 2019-08-17
Accepted: 2019-09-27

Abstract

Background: At first sight, the issue of terminology in morphological sciences may seem as “closed and changeless chapter”, as many of the structures within the human body have been known for centuries. However, the exact opposite is true. Terminologia Histologica: International Terms for Human Cytology and Histology published under the Federative International Programme on Anatomical Terminology in 2008 is a new standard in human cell and tissue terminology. The list of items in the first and still valid official nomenclature of cellular and tissue structures, the Terminologia Histologica (TH), is the best and most extensive of all the histological nomenclatures ever issued.

Materials and methods: The aim of this article is a systematic and in-depth analysis of the current internationally accepted nomenclature TH, with focus on important histological structures which are missing in this first edition. Some should be incorporated just for the sake of completeness and consistence, others are purely absent terms for individual structures or some are recently described new tissue structures.

Results: We also discuss about a question, how to deal with the issue of eponyms. Eponyms reflect medicine’s rich and colourful history. Although they have not been considered official terms in the anatomical nomenclature since 1955, they are still widely used in clinical practice.

Conclusions: We hope that this opinion article will develop a wide scientific discussion before the publication of the second edition, so perhaps the mentioned minor flaws will be corrected, so the new edition of the TH will become truly an internationally accepted communication tool for all histologists, histopathologists and anatomists.

Abstract

Background: At first sight, the issue of terminology in morphological sciences may seem as “closed and changeless chapter”, as many of the structures within the human body have been known for centuries. However, the exact opposite is true. Terminologia Histologica: International Terms for Human Cytology and Histology published under the Federative International Programme on Anatomical Terminology in 2008 is a new standard in human cell and tissue terminology. The list of items in the first and still valid official nomenclature of cellular and tissue structures, the Terminologia Histologica (TH), is the best and most extensive of all the histological nomenclatures ever issued.

Materials and methods: The aim of this article is a systematic and in-depth analysis of the current internationally accepted nomenclature TH, with focus on important histological structures which are missing in this first edition. Some should be incorporated just for the sake of completeness and consistence, others are purely absent terms for individual structures or some are recently described new tissue structures.

Results: We also discuss about a question, how to deal with the issue of eponyms. Eponyms reflect medicine’s rich and colourful history. Although they have not been considered official terms in the anatomical nomenclature since 1955, they are still widely used in clinical practice.

Conclusions: We hope that this opinion article will develop a wide scientific discussion before the publication of the second edition, so perhaps the mentioned minor flaws will be corrected, so the new edition of the TH will become truly an internationally accepted communication tool for all histologists, histopathologists and anatomists.

Get Citation

Keywords

histology; histopathology; terminology; nomenclature; Terminologia Histologica

About this article
Title

A plea for extension of the official nomenclature of the microscopic structure of human tissues and organs, the Terminologia Histologica

Journal

Folia Morphologica

Issue

Vol 79, No 3 (2020)

Pages

610-620

Published online

2019-10-09

DOI

10.5603/FM.a2019.0110

Pubmed

31617576

Bibliographic record

Folia Morphol 2020;79(3):610-620.

Keywords

histology
histopathology
terminology
nomenclature
Terminologia Histologica

Authors

I. Varga
D. Kachlík
M. Klein

References (71)
  1. Balko J, Tonar Z, Varga I. (Eds). Memorix Histology. Triton, Prague 2018.
  2. Bizheva K, Tan B, MacLellan B, et al. imaging of the palisades of Vogt and the limbal crypts with sub-micrometer axial resolution optical coherence tomography. Biomed Opt Express. 2017; 8(9): 4141–4151.
  3. Bunch PM. Anatomic eponyms in neuroradiology: head and neck. Acad Radiol. 2016; 23(10): 1319–1332.
  4. Burdan F, Dworzański W, Cendrowska-Pinkosz M, et al. Anatomical eponyms - unloved names in medical terminology. Folia Morphol. 2016; 75(4): 413–438.
  5. Carricondo F, Romero-Gómez B. The cochlear spiral ganglion neurons: the auditory portion of the VIII nerve. Anat Rec (Hoboken). 2019; 302(3): 463–471.
  6. Chaitow L. Telocytes: Connective tissue repair and communication cells. J Bodyw Mov Ther. 2017; 21(2): 231–233.
  7. Chmielewski PP, Domagała ZA. Terminologia Anatomica and its practical usage: pitfalls and how to avoid them. Folia Morphol. 2020; 79(2): 198–204.
  8. Chmielewski PP, Strzelec B. Should Terminologia Anatomica be revised and extended? A critical literature review. Folia Morphol. 2020; 79(1): 1–14.
  9. Chouchkov C. Cutaneous Receptors. Springer, Berlin Heidelberg 2012.
  10. Chvátal A, Kachlík D. Vincenc Alexandr Bohdálek (1801-1883): Czech anatomist and neuroscientist of the nineteenth century. J Hist Neurosci. 2017; 26(2): 125–139.
  11. FCAT. Terminologia Anatomica. Thieme Verlag, Stuttgart 1998.
  12. FIPAT. Terminologia Embryologica, 2nd Ed. http://fipat.library.dal.ca/TE2/, 2017 .
  13. FIPAT. Terminologia Histologica: International Terms for Human Cytology and Histology. Lippincott Williams & Wilkins, Baltimore 2008.
  14. FIPAT Terminologia Neuroatomica http://fipat library dal ca/TNA, 2017 .
  15. Flickinger CJ, Bush LA, Howards SS, et al. Distribution of leukocytes in the epithelium and interstitium of four regions of the Lewis rat epididymis. Anat Rec. 1997; 248(3): 380–390, doi: 10.1002/(SICI)1097-0185(199707)248:3<380::AID-AR11>3.0.CO;2-L.
  16. Gaeta M, Bandera F, Tassinari F, et al. Is epicardial fat depot associated with atrial fibrillation? A systematic review and meta-analysis. Europace. 2017; 19(5): 747–752.
  17. Goldberg MF, Bron AJ. Limbal palisades of Vogt. Trans Am Ophthalmol Soc. 1982; 80: 155–171.
  18. Gonzalez G, Sasamoto Y, Ksander BR, et al. Limbal stem cells: identity, developmental origin, and therapeutic potential. Wiley Interdiscip Rev Dev Biol. 2018; 7(2).
  19. Greene CA, Misra SL, Lee H, et al. The sheep cornea: structural and clinical characteristics. Curr Eye Res. 2018; 43(12): 1432–1438.
  20. Gruzdeva O, Uchasova E, Dyleva Y, et al. Relationship between epicardial and perivascular fatty tissue and adipokine-cytokine level in coronary artery disease patients. PLoS One. 2019; 14(6): e0208156.
  21. Hu Bo, Simon-Keller K, Küffer S, et al. Myf5 and Myogenin in the development of thymic myoid cells - Implications for a murine in vivo model of myasthenia gravis. Exp Neurol. 2016; 277: 76–85.
  22. Hunt JL, Lynn AAA. Histologic features of surgically removed fallopian tubes. Arch Pathol Lab Med. 2002; 126(8): 951–955, doi: 10.1043/0003-9985(2002)126<0951:HFOSRT>2.0.CO;2.
  23. Iancu CB, Rusu MC, Mogoantă L, et al. Myocardial Telocyte-Like Cells: A Review Including New Evidence. Cells Tissues Organs. 2018; 206(1-2): 16–25.
  24. Jeppson PC, Balgobin S, Washington BB, et al. Society of Gynecologic Surgeons Pelvic Anatomy Group. Recommended standardized terminology of the anterior female pelvis based on a structured medical literature review. Am J Obstet Gynecol. 2018; 219(1): 26–39.
  25. Kachlik D, Baca V, Bozdechova I, et al. Anatomical terminology and nomenclature: past, present and highlights. Surg Radiol Anat. 2008; 30(6): 459–466.
  26. Kachlík D, Musil V, Baca V. A plea for extension of the anatomical nomenclature. Part 1: Nervous system and senses. Folia Morphol. 2017; 76(2): 168–177.
  27. Kachlik D, Musil V, Baca V. Contribution to the anatomical nomenclature concerning general anatomy and anatomical variations. Surg Radiol Anat. 2016; 38(7): 757–765.
  28. Kachlik D, Musil V, Baca V. Contribution to the anatomical nomenclature concerning upper limb anatomy. Surg Radiol Anat. 2017; 39(4): 405–417.
  29. Kachlik D, Musil V, Baca V. Contribution to the anatomical nomenclature concerning lower limb anatomy. Surg Radiol Anat. 2018; 40(5): 537–562.
  30. Kinose S, Kanaya Y, Kawasaki Y, et al. Anatomic characterization of the radial and ulnar nutrient arteries in humans. Ann Anat. 2018; 216: 23–28.
  31. Kojima M, Nakamura S, Ichimura K, et al. Centroblastic and centroblastic/centrocytic lymphoma associated with a prominent epithelioid granulomatous response: a clinicopathologic study of 50 cases. Mod Pathol. 2002; 15(7): 750–758.
  32. Kondo A, Kaestner KH. Emerging diverse roles of telocytes. Development. 2019; 146(14).
  33. Krmpotić-Nemanić J, Vinter I. Missing and incorrect terms in terminologia anatomica (1998). Ann Anat. 2003; 185(4): 387–388.
  34. Krstic RV. Illustrated Encyclopedia of Human Histology. Springer, Berlin Heidelberg 2012.
  35. Kucharzik T, Lügering N, Rautenberg K, et al. Role of M cells in intestinal barrier function. Ann N Y Acad Sci. 2000; 915: 171–183.
  36. Kurtz A. Endocrine functions of the renal interstitium. Pflugers Arch. 2017; 469(7-8): 869–876.
  37. Liebermann-Meffert D, White H, Vaubel E. (Eds). The Greater OMENTUM. Anatomy, Physiology, Pathology, Surgery with an Historical Survey. Springer Verlag, Berlin 1983.
  38. Loewenstein WR. Principles of Receptor Physiology. Springer, Berlin Heidelberg 2013.
  39. MacDonald DM, Schmitt D. Ultrastructure of the human mucocutaneous end organ. J Invest Dermatol. 1979; 72(4): 181–186.
  40. Mannis MJ, Holland EJ. Cornea E-Book. Elsevier Health Sciences, 2016 .
  41. Marini M, Manetti M, Rosa I, et al. Telocytes in human fetal skeletal muscle interstitium during early myogenesis. Acta Histochem. 2018; 120(5): 397–404.
  42. Musil V, Blankova A, Baca V. A plea for an extension of the anatomical nomenclature: The locomotor system. Bosn J Basic Med Sci. 2018; 18(2): 117–125.
  43. Musil V, Blankova A, Dvorakova V, et al. A plea for an extension of the anatomical nomenclature: Organ systems. Bosn J Basic Med Sci. 2019; 19(1): 1–13.
  44. Paul PG, Koshy AK, Thomas T. Walthard cell nests on laparoscopy. J Minim Invasive Gynecol. 2006; 13(6): 499.
  45. Pelosi G, Fabbri A, Cossa M, et al. What clinicians are asking pathologists when dealing with lung neuroendocrine neoplasms? Semin Diagn Pathol. 2015; 32(6): 469–479.
  46. Petrini M, Alì M, Cannaò PM, et al. Epicardial adipose tissue volume in patients with coronary artery disease or non-ischaemic dilated cardiomyopathy: evaluation with cardiac magnetic resonance imaging. Clin Radiol. 2019; 74(1): 81.e1–81.e7.
  47. Popescu LM, Faussone-Pellegrini MS. TELOCYTES: a case of serendipity: the winding way from Interstitial Cells of Cajal (ICC), via Interstitial Cajal-Like Cells (ICLC) to TELOCYTES. J Cell Mol Med. 2010; 14(4): 729–740.
  48. Robaire B, Hinton BT, Orgebin-Crist MC. Chapter 22 - The Epididymis. Pp. 1071-1148. In. Neill JD. (Ed). Knobil and Neill's Physiology of Reproduction. 3rd Edition. Academic Press 2006.
  49. Rosen CA, Leden H, Ossoff RH, Simpson B. Operative Techniques in Laryngology. Springer, Berlin Heidelberg 2008.
  50. Rusu MC, Hostiuc S. Critical review: Cardiac telocytes vs cardiac lymphatic endothelial cells. Ann Anat. 2019; 222: 40–54.
  51. Senior A. Friedrich Berthold Reinke (1862-1919): brilliant yet troubled anatomist of the vocal fold. J Laryngol Otol. 2015; 129(11): 1053–1057.
  52. Sepehri Shamloo A, Schoene K, Stauber A, et al. Epicardial adipose tissue thickness as an independent predictor of ventricular tachycardia recurrence following ablation. Heart Rhythm. 2019; 16(10): 1492–1498.
  53. Stecco C, Corradin M, Macchi V, et al. Plantar fascia anatomy and its relationship with Achilles tendon and paratenon. J Anat. 2013; 223(6): 665–676.
  54. Strzelec B, Chmielewski PP, Gworys B. The Terminologia Anatomica matters: examples from didactic, scientific, and clinical practice. Folia Morphol. 2017; 76(3): 340–347.
  55. Ten Donkelaar HJ, Broman J, Neumann PE, et al. Towards a Terminologia Neuroanatomica. Clin Anat. 2017; 30(2): 145–155.
  56. Ten Donkelaar HJ, Kachlik D, Tubbs RS. An Illustrated Terminologia Neuroanatomica. A Concise Encyclopedia of Human Neuroanatomy. Springer, 2018 .
  57. Thomas CJ, Woods RL, Evans RG, et al. Evidence for a renomedullary vasodepressor hormone. Clin Exp Pharmacol Physiol. 1996; 23(9): 777–785.
  58. Toader OD, Rusu MC, Mogoantă L, et al. An immunohistochemical study of gastric mucosa and critical review indicate that the subepithelial telocytes are prelymphatic endothelial cells. Medicina (Kaunas). 2019; 55(7).
  59. Varga I, Blankova A, Konarik M, et al. The Terminologia Histologica after 10years: Inconsistencies, mistakes, and new proposals. Ann Anat. 2018; 219: 65–75.
  60. Varga I, Bódi I, Kachlík D, et al. The enigmatic thymic myoid cells – their 130 years of history, embryonic origin, function and clinical significance. Biologia. 2019; 74(5): 521–531.
  61. Varga I, Danišovič Ľ, Kachlík D, et al. Zoological terms in the human histological nomenclature Terminologia Histologica. What we think, what we know, and what we think we know. Biologia. 2019.
  62. Varga I, Gálfiová P, Blanková A, et al. Terminologia Histologica 10 years on: some disputable terms in need of discussion and recent developments. Ann Anat. 2019; 226: 16–22.
  63. Varga I, Kachlík D, Žišková M, et al. Lymphatic lacunae of the mucosal folds of human uterine tubes - A rediscovery of forgotten structures and their possible role in reproduction. Ann Anat. 2018; 219: 121–128.
  64. Varga I, Kyselovič J, Danišovič Ľ, et al. Recently discovered interstitial cells termed telocytes: distinguishing cell-biological and histological facts from fictions. Biologia. 2018; 74(2): 195–203.
  65. Varga I, Miko M, Kachlík D, et al. How many cell types form the epithelial lining of the human uterine tubes? Revision of the histological nomenclature of the human tubal epithelium. Ann Anat. 2019; 224: 73–80.
  66. Varga I, Polák Š, Kyselovič J, et al. Recently discovered interstitial cell population of telocytes: distinguishing facts from fiction regarding their role in the pathogenesis of diverse diseases called "telocytopathies". Medicina (Kaunas). 2019; 55(2).
  67. Verbrugghe P, Kujala P, Waelput W, et al. Clusterin in human gut-associated lymphoid tissue, tonsils, and adenoids: localization to M cells and follicular dendritic cells. Histochem Cell Biol. 2008; 129(3): 311–320.
  68. Villarroel MA, Lizana PA. Descriptive characteristics of the area of origin of the deltoid muscle on the human clavicle. Is it necessary to include new terms in the Terminologia Anatomica? Homo. 2018; 69(4): 198–202.
  69. Winkelmann RK. The erogenous zones: their nerve supply and its significance. Proc Staff Meet Mayo Clin. 1959; 34(2): 39–47.
  70. Witter K, Tonar Z, Schöpper H. How many Layers has the Adventitia? - Structure of the Arterial Tunica Externa Revisited. Anat Histol Embryol. 2017; 46(2): 110–120.
  71. Xu MY, Ye ZS, Song XT, et al. Differences in the cargos and functions of exosomes derived from six cardiac cell types: a systematic review. Stem Cell Res Ther. 2019; 10(1): 194.

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By  "Via Medica sp. z o.o." sp.k., Świętokrzyska 73, 80–180 Gdańsk, Poland

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl