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Ahead of Print
ORIGINAL ARTICLES
Published online: 2018-12-20
Submitted: 2018-10-23
Accepted: 2018-12-07
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Evaluation of relationship between middle cerebellar peduncle asymmetry and dominant hand by diffusion tensor imaging

Gökhan Polat
DOI: 10.5603/FM.a2018.0116
·
Pubmed: 30575006

open access

Ahead of Print
ORIGINAL ARTICLES
Published online: 2018-12-20
Submitted: 2018-10-23
Accepted: 2018-12-07

Abstract

Background: We aimed to evaluate middle cerebellar peduncle (MCP) asymmetry by diffusion tensor imaging (DTI) according to the dominant hand.

Materials and methods: Sixty-four volunteers who met the exclusion and inclusion criteria were prospectively evaluated by DTI. Circular voxels of interest were drawn at the right and left MCP levels for all volunteers. The software automatically calculated the median values of fractional anisotropy (FA), mean diffusivity (MD), and number of fibers (NF). The volunteers were categorized as the right-handed (n=44) and left-handed (n=20) groups using the Dellatolas test. The mean values of FA, MD and NF were statistically compared between the two sides and the two groups.

Results: In both groups, the mean value of FA for the right MCP was significantly higher than the left MCP (p=0.0016 and p=0.0032 for the right- and left-handed groups, respectively). In both groups, no significant difference was observed between the right and left MCPs in terms of MD and NF(p=0.75, p=0.69 and p=0.96,p= 0.46,respectively). There was also no statistically significant difference between the groups for the mean values of FA, MD and NF of each MCP (p=0.74, 0.26 and 0.26, respectively for the right MCP and p= 0.78, 0.37 and 0.54, respectively for the left MCP).

Conclusions: There is an asymmetry between the mean FA values of the right and left MCP. However, this asymmetry is independent of the dominant hand.

Abstract

Background: We aimed to evaluate middle cerebellar peduncle (MCP) asymmetry by diffusion tensor imaging (DTI) according to the dominant hand.

Materials and methods: Sixty-four volunteers who met the exclusion and inclusion criteria were prospectively evaluated by DTI. Circular voxels of interest were drawn at the right and left MCP levels for all volunteers. The software automatically calculated the median values of fractional anisotropy (FA), mean diffusivity (MD), and number of fibers (NF). The volunteers were categorized as the right-handed (n=44) and left-handed (n=20) groups using the Dellatolas test. The mean values of FA, MD and NF were statistically compared between the two sides and the two groups.

Results: In both groups, the mean value of FA for the right MCP was significantly higher than the left MCP (p=0.0016 and p=0.0032 for the right- and left-handed groups, respectively). In both groups, no significant difference was observed between the right and left MCPs in terms of MD and NF(p=0.75, p=0.69 and p=0.96,p= 0.46,respectively). There was also no statistically significant difference between the groups for the mean values of FA, MD and NF of each MCP (p=0.74, 0.26 and 0.26, respectively for the right MCP and p= 0.78, 0.37 and 0.54, respectively for the left MCP).

Conclusions: There is an asymmetry between the mean FA values of the right and left MCP. However, this asymmetry is independent of the dominant hand.

Get Citation

Keywords

middle cerebellar peduncle, diffusion tensor imaging, fractional anisotropy, dominant hand

About this article
Title

Evaluation of relationship between middle cerebellar peduncle asymmetry and dominant hand by diffusion tensor imaging

Journal

Folia Morphologica

Issue

Ahead of Print

Published online

2018-12-20

DOI

10.5603/FM.a2018.0116

Pubmed

30575006

Keywords

middle cerebellar peduncle
diffusion tensor imaging
fractional anisotropy
dominant hand

Authors

Gökhan Polat

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