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ORIGINAL ARTICLES
Published online: 2018-10-19
Submitted: 2018-08-31
Accepted: 2018-10-08
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Age-related structural-mechanical property changes in human peroneus longus muscle

Apichaya Niyomchan, Benjaporn Panichareon, Akkradate Siriphorn, Tulaporn Wongtawatchai
DOI: 10.5603/FM.a2018.0102
·
Pubmed: 30371930

open access

Ahead of Print
ORIGINAL ARTICLES
Published online: 2018-10-19
Submitted: 2018-08-31
Accepted: 2018-10-08

Abstract

Functional impairment of the muscle-tendon unit is one of the most remarkable effects of aging. The function of the peroneus longus muscle is to stabilize the foot and ankle joint. A deterioration of the structural and mechanical properties of this muscle can potentially lead to foot problems in older adults. This study aimed to investigate the effects of age on structural, histological, and mechanical features in peroneus longus muscle samples taken from embalmed cadavers of two different age groups; young adult (30-60 years) and old adult (over 60 years). The mechanical property was analyzed through the results of cross-sectional area, tensile, tensile stress, and modulus of elasticity. The arrangement of the collagen in the perimysium and tendon was examined by scanning electron microscopy. Fatty infiltration within the musculotendinous junction was evaluated by Masson’ trichrome stained muscle sections. This study thus provides evidence that there are indeed age-induced mechanical property changes in the peroneus longus muscle, which include reductions in the tensile force, tensile stress, and modulus of elasticity, and is related to the malformation of collagen fibrils and the massive fat accumulation in the musculotendinous junction. These alterations may further result in a reduction of muscle strength and quality in an older person.

Abstract

Functional impairment of the muscle-tendon unit is one of the most remarkable effects of aging. The function of the peroneus longus muscle is to stabilize the foot and ankle joint. A deterioration of the structural and mechanical properties of this muscle can potentially lead to foot problems in older adults. This study aimed to investigate the effects of age on structural, histological, and mechanical features in peroneus longus muscle samples taken from embalmed cadavers of two different age groups; young adult (30-60 years) and old adult (over 60 years). The mechanical property was analyzed through the results of cross-sectional area, tensile, tensile stress, and modulus of elasticity. The arrangement of the collagen in the perimysium and tendon was examined by scanning electron microscopy. Fatty infiltration within the musculotendinous junction was evaluated by Masson’ trichrome stained muscle sections. This study thus provides evidence that there are indeed age-induced mechanical property changes in the peroneus longus muscle, which include reductions in the tensile force, tensile stress, and modulus of elasticity, and is related to the malformation of collagen fibrils and the massive fat accumulation in the musculotendinous junction. These alterations may further result in a reduction of muscle strength and quality in an older person.

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Keywords

aging, collagen, musculotendinous junction, tendon

About this article
Title

Age-related structural-mechanical property changes in human peroneus longus muscle

Journal

Folia Morphologica

Issue

Ahead of Print

Published online

2018-10-19

DOI

10.5603/FM.a2018.0102

Pubmed

30371930

Keywords

aging
collagen
musculotendinous junction
tendon

Authors

Apichaya Niyomchan
Benjaporn Panichareon
Akkradate Siriphorn
Tulaporn Wongtawatchai

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