open access

Vol 75, No 2 (2016)
ORIGINAL ARTICLES
Published online: 2015-09-17
Submitted: 2015-06-10
Accepted: 2015-07-13
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Lymphatic vessels around the uterus: D2-40 (podoplandin) immunohistochemistry using elderly cadavers

H. Sasaki, Z. W. Jin, Y. L. Liu, Y. Jin, G. Murakami, S.-I. Abe
DOI: 10.5603/FM.a2015.0083
·
Pubmed: 26383507
·
Folia Morphol 2016;75(2):232-239.

open access

Vol 75, No 2 (2016)
ORIGINAL ARTICLES
Published online: 2015-09-17
Submitted: 2015-06-10
Accepted: 2015-07-13

Abstract

Using D2-40 immunohistochemistry, we examined the morphology of lymphatic vessels (LVs) in, along and around the uterus of 10 donated female cadavers (mean age, 85 years). All these women had 1 or 2 children with vaginal delivery, but the other obstetrics information was unknown. When compared with the bladder, vagina and the subperitoneal tissue, the percentage area of LVs in a 3 × 2 mm square including the hot spot was extremely high along the uterine artery and superficial uterine vein, in spite of the silent physiology of the elderly uterus. Notably, the LVs along the uterine artery and superficial uterine vein were highly dilated and embedded in the tight connective tissue around the artery and vein. In contrast, the LVs were separated from the artery and vein in the so-called vesico- -uterine ligament. Thus, surgical separation of the LVs from the artery and vein, i.e., skeletonisation, appears very difficult along the uterine artery and superficial uterine vein. This may become a major factor limiting the future application of robot-assisted surgery for uterine cancers.

Abstract

Using D2-40 immunohistochemistry, we examined the morphology of lymphatic vessels (LVs) in, along and around the uterus of 10 donated female cadavers (mean age, 85 years). All these women had 1 or 2 children with vaginal delivery, but the other obstetrics information was unknown. When compared with the bladder, vagina and the subperitoneal tissue, the percentage area of LVs in a 3 × 2 mm square including the hot spot was extremely high along the uterine artery and superficial uterine vein, in spite of the silent physiology of the elderly uterus. Notably, the LVs along the uterine artery and superficial uterine vein were highly dilated and embedded in the tight connective tissue around the artery and vein. In contrast, the LVs were separated from the artery and vein in the so-called vesico- -uterine ligament. Thus, surgical separation of the LVs from the artery and vein, i.e., skeletonisation, appears very difficult along the uterine artery and superficial uterine vein. This may become a major factor limiting the future application of robot-assisted surgery for uterine cancers.

Get Citation

Keywords

lymphatic vessels, artery, uterus, vagina, connective tissue

About this article
Title

Lymphatic vessels around the uterus: D2-40 (podoplandin) immunohistochemistry using elderly cadavers

Journal

Folia Morphologica

Issue

Vol 75, No 2 (2016)

Pages

232-239

Published online

2015-09-17

DOI

10.5603/FM.a2015.0083

Pubmed

26383507

Bibliographic record

Folia Morphol 2016;75(2):232-239.

Keywords

lymphatic vessels
artery
uterus
vagina
connective tissue

Authors

H. Sasaki
Z. W. Jin
Y. L. Liu
Y. Jin
G. Murakami
S.-I. Abe

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