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Vol 64, No 1 (2005)
Review article
Submitted: 2012-02-06
Published online: 2004-12-10
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Morphological studies in modern teratological investigations

F. Burdan, J. Szumiło, J. Dudka, R. Klepacz, M. Błaszczak, M. Solecki, A. Korobowicz, A. Chałas, J. Klepacki, M. Palczak, A. Żuchnik-Wrona, A. Hadała-Kiś, Z. Urbanowicz, Z. Wójtowicz
Folia Morphol 2005;64(1):1-8.

open access

Vol 64, No 1 (2005)
REVIEW ARTICLES
Submitted: 2012-02-06
Published online: 2004-12-10

Abstract

Despite the variety of modern molecular techniques available, examination of foetal anatomy is still a fundamental part of teratological studies in evaluating the developmental toxicity of xenobiotics or other non-chemical factors. The article presents contemporary methods of embryotoxicity and foetotoxicity assessment. A single alizarin red S and double alcian blue followed by alizarin red S staining, as well as various methods of soft tissue examination are discussed.

Abstract

Despite the variety of modern molecular techniques available, examination of foetal anatomy is still a fundamental part of teratological studies in evaluating the developmental toxicity of xenobiotics or other non-chemical factors. The article presents contemporary methods of embryotoxicity and foetotoxicity assessment. A single alizarin red S and double alcian blue followed by alizarin red S staining, as well as various methods of soft tissue examination are discussed.

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Keywords

bone; cartilage; developmental toxicity; foetus; methods; risk assessment; soft tissue examination; skeleton; staining; visceral examination

About this article
Title

Morphological studies in modern teratological investigations

Journal

Folia Morphologica

Issue

Vol 64, No 1 (2005)

Article type

Review article

Pages

1-8

Published online

2004-12-10

Page views

613

Article views/downloads

2298

Bibliographic record

Folia Morphol 2005;64(1):1-8.

Keywords

bone
cartilage
developmental toxicity
foetus
methods
risk assessment
soft tissue examination
skeleton
staining
visceral examination

Authors

F. Burdan
J. Szumiło
J. Dudka
R. Klepacz
M. Błaszczak
M. Solecki
A. Korobowicz
A. Chałas
J. Klepacki
M. Palczak
A. Żuchnik-Wrona
A. Hadała-Kiś
Z. Urbanowicz
Z. Wójtowicz

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