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Vol 58, No 2 (2020)
ORIGINAL PAPERS
Published online: 2020-06-02
Submitted: 2020-01-10
Accepted: 2020-04-29
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A close neuroanatomical relationship between the enkephalinergic (methionine-enkephalin) and tachykininergic (substance P) systems in the alpaca diencephalon

Pablo Sánchez, Manuel Lisardo Sánchez, Arturo Mangas, Luís Ángel Aguilar, Rafael Coveñas
DOI: 10.5603/FHC.a2020.0007
·
Pubmed: 32412087
·
Folia Histochem Cytobiol 2020;58(2):135-146.

open access

Vol 58, No 2 (2020)
ORIGINAL PAPERS
Published online: 2020-06-02
Submitted: 2020-01-10
Accepted: 2020-04-29

Abstract

Introduction. In the alpaca diencephalon, the distribution of immunoreactive cell bodies and fibers containing methionine-enkephalin (MET) or substance P (SP) has been studied.

Material and methods. The immunohistochemical study was performed by standard method on the diencephalon of four male alpacas that lived at sea level.

Results. Nerve fibers containing MET or SP were widely distributed in the thalamus and hypothalamus. METand SP-immunoreactive fibers showed a similar distribution in the whole diencephalon. Immunoreactive cell bodies containing MET or SP were only observed in the hypothalamus. The distribution of MET-immunoreactive cell bodies was more widespread than that observed for cell bodies containing SP.

Conclusions. A close neuroanatomical relationship between the tachykininergic (SP) and enkephalinergic (MET) systems was observed in the whole diencephalon suggestive of the existence of multiple physiological interactions between both systems.

Abstract

Introduction. In the alpaca diencephalon, the distribution of immunoreactive cell bodies and fibers containing methionine-enkephalin (MET) or substance P (SP) has been studied.

Material and methods. The immunohistochemical study was performed by standard method on the diencephalon of four male alpacas that lived at sea level.

Results. Nerve fibers containing MET or SP were widely distributed in the thalamus and hypothalamus. METand SP-immunoreactive fibers showed a similar distribution in the whole diencephalon. Immunoreactive cell bodies containing MET or SP were only observed in the hypothalamus. The distribution of MET-immunoreactive cell bodies was more widespread than that observed for cell bodies containing SP.

Conclusions. A close neuroanatomical relationship between the tachykininergic (SP) and enkephalinergic (MET) systems was observed in the whole diencephalon suggestive of the existence of multiple physiological interactions between both systems.

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Keywords

Lama pacos; hypothalamus; thalamus; methionine-enkephalin; substance P; IHC

About this article
Title

A close neuroanatomical relationship between the enkephalinergic (methionine-enkephalin) and tachykininergic (substance P) systems in the alpaca diencephalon

Journal

Folia Histochemica et Cytobiologica

Issue

Vol 58, No 2 (2020)

Pages

135-146

Published online

2020-06-02

DOI

10.5603/FHC.a2020.0007

Pubmed

32412087

Bibliographic record

Folia Histochem Cytobiol 2020;58(2):135-146.

Keywords

Lama pacos
hypothalamus
thalamus
methionine-enkephalin
substance P
IHC

Authors

Pablo Sánchez
Manuel Lisardo Sánchez
Arturo Mangas
Luís Ángel Aguilar
Rafael Coveñas

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