open access

Vol 49, No 3 (2011)
Review paper
Submitted: 2012-01-05
Published online: 2011-10-28
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Stem cells and skin regeneration

Marzena Staniszewska, Sylwia Słuczanowska-Głąbowska, Justyna Drukała
DOI: 10.5603/FHC.2011.0053
·
Folia Histochem Cytobiol 2011;49(3):375-380.

open access

Vol 49, No 3 (2011)
REVIEW
Submitted: 2012-01-05
Published online: 2011-10-28

Abstract

Stem cells represent a great hope for regenerative medicine. In adult life, stem cell deposits are kept in organ niches; the need for tissue or organ regeneration mobilizes stem cells via the SDF-1-CXCR4 regulation axis. Constant regeneration of the skin is achieved due to stem cell differentiation within the epidermis and the hair follicle; thus, skin may serve as an excellent source of stem cells. This is of paramount importance in the treatment of chronic skin wounds and burns. (Folia Histochemica et Cytobiologica 2011; Vol. 49, No. 3, pp. 375–380)

Abstract

Stem cells represent a great hope for regenerative medicine. In adult life, stem cell deposits are kept in organ niches; the need for tissue or organ regeneration mobilizes stem cells via the SDF-1-CXCR4 regulation axis. Constant regeneration of the skin is achieved due to stem cell differentiation within the epidermis and the hair follicle; thus, skin may serve as an excellent source of stem cells. This is of paramount importance in the treatment of chronic skin wounds and burns. (Folia Histochemica et Cytobiologica 2011; Vol. 49, No. 3, pp. 375–380)
Get Citation

Keywords

stem cells; epidermal stem cells; VSELs; CXCR4 receptors; wound

About this article
Title

Stem cells and skin regeneration

Journal

Folia Histochemica et Cytobiologica

Issue

Vol 49, No 3 (2011)

Article type

Review paper

Pages

375-380

Published online

2011-10-28

DOI

10.5603/FHC.2011.0053

Bibliographic record

Folia Histochem Cytobiol 2011;49(3):375-380.

Keywords

stem cells
epidermal stem cells
VSELs
CXCR4 receptors
wound

Authors

Marzena Staniszewska
Sylwia Słuczanowska-Głąbowska
Justyna Drukała

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