open access

Vol 50, No 4 (2012)
Brief communication
Submitted: 2012-09-29
Accepted: 2012-11-04
Published online: 2012-12-23
Get Citation

The effect of chronic alcohol intoxication and smoking on the output of salivary immunoglobulin A

Napoleon Waszkiewicz, Anna Zalewska, Slawomir Dariusz Szajda, Magdalena Waszkiewicz, Agata Szulc, Alina Kepka, Beata Konarzewska, Alina Minarowska, Beata Zalewska-Szajda, Dorota Wilamowska, Danuta Waszkiel, Jerzy Robert Ladny, Krzysztof Zwierz
DOI: 10.5603/FHC.2012.0085
·
Folia Histochem Cytobiol 2012;50(4):605-608.

open access

Vol 50, No 4 (2012)
Short Communication
Submitted: 2012-09-29
Accepted: 2012-11-04
Published online: 2012-12-23

Abstract

It was investigated the effect of chronic alcohol intoxication and smoking, on the output of salivary immunoglobulin A (IgA). In the study participated 37 volunteers: 17 male smoking patients after chronic alcohol intoxication (AS) and 20 control nonsmoking male social drinkers (CNS). The DMFT index (decayed, missing, or filled teeth), gingival index (GI) and papilla bleeding index (PBI) were assessed. Levels of IgA were determined by the enzyme-linked immunosorbent method. There were significantly decreased salivary flow (SF) and IgA output in AS, when compared to the CNS. There were no significant correlations between amount of alcohol/cigarettes as well as  duration of alcohol intoxication/smoking, and SF or IgA output, and between IgA and SF. Gingival index was significantly higher in AS than in CNS, and inversely correlated with IgA. It is more probable that SF and IgA decrease, are the result of ethanol action than smoking. Worse periodontal state in smoking alcohol dependent persons than in controls, may be the result of lower IgA protection of the oral cavity due to its decreased output.

Abstract

It was investigated the effect of chronic alcohol intoxication and smoking, on the output of salivary immunoglobulin A (IgA). In the study participated 37 volunteers: 17 male smoking patients after chronic alcohol intoxication (AS) and 20 control nonsmoking male social drinkers (CNS). The DMFT index (decayed, missing, or filled teeth), gingival index (GI) and papilla bleeding index (PBI) were assessed. Levels of IgA were determined by the enzyme-linked immunosorbent method. There were significantly decreased salivary flow (SF) and IgA output in AS, when compared to the CNS. There were no significant correlations between amount of alcohol/cigarettes as well as  duration of alcohol intoxication/smoking, and SF or IgA output, and between IgA and SF. Gingival index was significantly higher in AS than in CNS, and inversely correlated with IgA. It is more probable that SF and IgA decrease, are the result of ethanol action than smoking. Worse periodontal state in smoking alcohol dependent persons than in controls, may be the result of lower IgA protection of the oral cavity due to its decreased output.

Get Citation
About this article
Title

The effect of chronic alcohol intoxication and smoking on the output of salivary immunoglobulin A

Journal

Folia Histochemica et Cytobiologica

Issue

Vol 50, No 4 (2012)

Article type

Brief communication

Pages

605-608

Published online

2012-12-23

DOI

10.5603/FHC.2012.0085

Bibliographic record

Folia Histochem Cytobiol 2012;50(4):605-608.

Authors

Napoleon Waszkiewicz
Anna Zalewska
Slawomir Dariusz Szajda
Magdalena Waszkiewicz
Agata Szulc
Alina Kepka
Beata Konarzewska
Alina Minarowska
Beata Zalewska-Szajda
Dorota Wilamowska
Danuta Waszkiel
Jerzy Robert Ladny
Krzysztof Zwierz

Regulations

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl