open access

Vol 50, No 4 (2012)
Original paper
Submitted: 2012-01-18
Accepted: 2012-04-27
Published online: 2012-12-23
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Mast cells evaluation in meningioma of various grades

Joanna Reszeć, Adam Hermanowicz, Jan Kochanowicz, Grzegorz Turek, Zenon Mariak, Lech Chyczewski
DOI: 10.5603/FHC.2012.0076
·
Folia Histochem Cytobiol 2012;50(4):542-546.

open access

Vol 50, No 4 (2012)
ORIGINAL PAPERS
Submitted: 2012-01-18
Accepted: 2012-04-27
Published online: 2012-12-23

Abstract

Introduction: Meningioma is a heterogenous group of primary brain tumors. The progression or recurrence is relatively very common; however there is lack of prognostic factors which may indicate those events. The aim of the study was to evaluate the presence of mast cells within the low grade and high grade meningiomas.

Material and Methods: The immunohistochemical reaction was done. The tryptase expression was estimated in slides of meningiomas of various grades in 10 random fields under the light microscope.

Results: The expression of tryptase was observed in 31,8% low grade meningiomas and in 85,9% high grade meningiomas. The immunostaining was observed next to the blood vessels.

Conclusion: The presence of mast cells might be a significant prognostic factor for the recurrence or the worse prognosis of meningiomas.

Abstract

Introduction: Meningioma is a heterogenous group of primary brain tumors. The progression or recurrence is relatively very common; however there is lack of prognostic factors which may indicate those events. The aim of the study was to evaluate the presence of mast cells within the low grade and high grade meningiomas.

Material and Methods: The immunohistochemical reaction was done. The tryptase expression was estimated in slides of meningiomas of various grades in 10 random fields under the light microscope.

Results: The expression of tryptase was observed in 31,8% low grade meningiomas and in 85,9% high grade meningiomas. The immunostaining was observed next to the blood vessels.

Conclusion: The presence of mast cells might be a significant prognostic factor for the recurrence or the worse prognosis of meningiomas.

Get Citation

Keywords

meningioma; mast cell; tryptase

About this article
Title

Mast cells evaluation in meningioma of various grades

Journal

Folia Histochemica et Cytobiologica

Issue

Vol 50, No 4 (2012)

Article type

Original paper

Pages

542-546

Published online

2012-12-23

DOI

10.5603/FHC.2012.0076

Bibliographic record

Folia Histochem Cytobiol 2012;50(4):542-546.

Keywords

meningioma
mast cell
tryptase

Authors

Joanna Reszeć
Adam Hermanowicz
Jan Kochanowicz
Grzegorz Turek
Zenon Mariak
Lech Chyczewski

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