open access

Vol 49, No 4 (2011)
Original paper
Submitted: 2012-01-16
Published online: 2012-01-16
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Videostroboscopic and morphological aspects of voice disturbances in patients with larynx atrophy and coexisting hypopharynx cancer

Bożena Kosztyła-Hojna, Anna Andrzejewska, Diana Moskal, Joanna Kasperuk, Dawid Falkowski, Marek Rogowski
DOI: 10.5603/FHC.2011.0090
·
Folia Histochem Cytobiol 2011;49(4):659-663.

open access

Vol 49, No 4 (2011)
ORIGINAL PAPERS
Submitted: 2012-01-16
Published online: 2012-01-16

Abstract

Vocal folds play a crucial role in voice production. The physiological vibrations of vocal folds depend on the unchanged multilayered structure of the vocal folds mucosa. Morphological changes of mucosa are the cause of voice quality disorders — dysphonia. The aim of this study was to determine the morphological base of dysphonia in patients with vocal folds atrophy. A group of 24 patients with larynx atrophy confirmed by endoscopic (VLS) and stroboscopic (VLSS) examination of the larynx was included in the study. The morphological assessment of the larynx mucosa was carried out with the use of the transmission electron microscopy (TEM). Ultramorphological examinations revealed changes in the epithelium, basal membrane and lamina propria of the vocal folds mucosa. An increased number of collagenous fibers, fibroblasts with signs of vacuolar degeneration inflammatory cells and a decreased number of blood vessels and pericytes were observed. Morphological changes found in the epithelium, basal membrane and lamina propria of the vocal folds mucosa were the cause of disorders of vocal folds vibrations registered in the stroboscopic examination of the larynx (VLSS). (Folia Histochemica et Cytobiologica 2011; Vol. 49, No. 4, pp. 659–663)

Abstract

Vocal folds play a crucial role in voice production. The physiological vibrations of vocal folds depend on the unchanged multilayered structure of the vocal folds mucosa. Morphological changes of mucosa are the cause of voice quality disorders — dysphonia. The aim of this study was to determine the morphological base of dysphonia in patients with vocal folds atrophy. A group of 24 patients with larynx atrophy confirmed by endoscopic (VLS) and stroboscopic (VLSS) examination of the larynx was included in the study. The morphological assessment of the larynx mucosa was carried out with the use of the transmission electron microscopy (TEM). Ultramorphological examinations revealed changes in the epithelium, basal membrane and lamina propria of the vocal folds mucosa. An increased number of collagenous fibers, fibroblasts with signs of vacuolar degeneration inflammatory cells and a decreased number of blood vessels and pericytes were observed. Morphological changes found in the epithelium, basal membrane and lamina propria of the vocal folds mucosa were the cause of disorders of vocal folds vibrations registered in the stroboscopic examination of the larynx (VLSS). (Folia Histochemica et Cytobiologica 2011; Vol. 49, No. 4, pp. 659–663)
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Keywords

larynx; vocal fold mucosa; larynx atrophy; lamina propria; videolaryngostroboscopy (VLSS); transmission electron microscopy (TEM)

About this article
Title

Videostroboscopic and morphological aspects of voice disturbances in patients with larynx atrophy and coexisting hypopharynx cancer

Journal

Folia Histochemica et Cytobiologica

Issue

Vol 49, No 4 (2011)

Article type

Original paper

Pages

659-663

Published online

2012-01-16

DOI

10.5603/FHC.2011.0090

Bibliographic record

Folia Histochem Cytobiol 2011;49(4):659-663.

Keywords

larynx
vocal fold mucosa
larynx atrophy
lamina propria
videolaryngostroboscopy (VLSS)
transmission electron microscopy (TEM)

Authors

Bożena Kosztyła-Hojna
Anna Andrzejewska
Diana Moskal
Joanna Kasperuk
Dawid Falkowski
Marek Rogowski

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