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Vol 14, No 4 (2019)
Report
Published online: 2018-09-14
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Novel synthesis of magnetic nanoparticles conjugation with perfluorocarbon nanobubbles for potential adjunct therapy of acute myocardial ischaemia

Mark C. Arokiaraj
DOI: 10.5603/FC.a2018.0095
·
Folia Cardiologica 2019;14(4):425-427.

open access

Vol 14, No 4 (2019)
Report
Published online: 2018-09-14

Abstract

Introduction. This study was performed in search of a novel adjunct agent for myocardial salvage in acute myocardial ischaemia. Methods and results. This is a report of conjugation between perfluorocarbon nanobubbles with multifunctional biocompatible magnetic nanoparticles. It was possible to synthesise the conjugation of multifunctional biocompatible magnetic nanoparticles with perfluorocarbon nanobubbles. The potential nano-size magnetic product could cross the deranged endothelial borders in the ischaemic penumbra regions, and could help in myocardial salvage. Furthermore, the particles could be focused to the target region using the magnetic micromesh technique. Conclusions. A conjugation between magnetic nanoparticles and PFC nano-bubbles is possible. Further studies need to be performed to explore the potential uses.

Abstract

Introduction. This study was performed in search of a novel adjunct agent for myocardial salvage in acute myocardial ischaemia. Methods and results. This is a report of conjugation between perfluorocarbon nanobubbles with multifunctional biocompatible magnetic nanoparticles. It was possible to synthesise the conjugation of multifunctional biocompatible magnetic nanoparticles with perfluorocarbon nanobubbles. The potential nano-size magnetic product could cross the deranged endothelial borders in the ischaemic penumbra regions, and could help in myocardial salvage. Furthermore, the particles could be focused to the target region using the magnetic micromesh technique. Conclusions. A conjugation between magnetic nanoparticles and PFC nano-bubbles is possible. Further studies need to be performed to explore the potential uses.
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Keywords

acute myocardial infarction, pharmacology, basic science research, hypoxia

About this article
Title

Novel synthesis of magnetic nanoparticles conjugation with perfluorocarbon nanobubbles for potential adjunct therapy of acute myocardial ischaemia

Journal

Folia Cardiologica

Issue

Vol 14, No 4 (2019)

Pages

425-427

Published online

2018-09-14

DOI

10.5603/FC.a2018.0095

Bibliographic record

Folia Cardiologica 2019;14(4):425-427.

Keywords

acute myocardial infarction
pharmacology
basic science research
hypoxia

Authors

Mark C. Arokiaraj

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