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Regular chromogranin A monitoring facilitated the early detection of a gastrointestinal neuroendocrine tumour in a patient with type 1 diabetes
Affiliations- Department of Internal Medicine and Haematology, Semmelweis University, Budapest, Hungary
- 1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary
- Department of Transplantation and Surgery, Semmelweis University, Budapest, 1082, Hungary
- Department of Obstetrics and Gynaecology, Medical University of Vienna, Vienna, Austria
- Molecular Medicine Research Group, Eotvos Lorand Research Network and Semmelweis University, Budapest, Hungary
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Abstract
Not required for Clinical Vignette.
Abstract
Not required for Clinical Vignette.
Keywords
chromogranin A; diabetes mellitus type 1; enterochromaffin-like cells; atrophic gastritis; neuroendocrine tumours
About this articleTitle
Regular chromogranin A monitoring facilitated the early detection of a gastrointestinal neuroendocrine tumour in a patient with type 1 diabetes
Journal
Issue
Article type
Clinical vignette
Pages
483-484
Published online
2020-08-27
Page views
878
Article views/downloads
508
DOI
10.5603/EP.a2020.0054
Pubmed
Bibliographic record
Endokrynol Pol 2020;71(5):483-484.
Keywords
chromogranin A
diabetes mellitus type 1
enterochromaffin-like cells
atrophic gastritis
neuroendocrine tumours
Authors
Zoltan Herold
Andrea Uhlyarik
Magdolna Herold
Peter Nagy
Gergely Denes Huszty
Klara Rosta
Marton Doleschall
Aniko Somogyi
References (5)- Wang R, Zheng-Pywell R, Chen HA, et al. Management of Gastrointestinal Neuroendocrine Tumors. Clin Med Insights Endocrinol Diabetes. 2019; 12: 1179551419884058.
- Herold Z, Doleschall M, Kovesdi A, et al. Chromogranin A and its role in the pathogenesis of diabetes mellitus. Endokrynol Pol. 2018; 69(5): 598–610.
- Herold Z, Herold M, Nagy P, et al. Serum chromogranin A level continuously rises with the progression of type 1 diabetes, and indicates the presence of both enterochromaffin-like cell hyperplasia and autoimmune gastritis. J Diabetes Investig. 2019 [Epub ahead of print].
- De Block CEM, Colpin G, Thielemans K, et al. Neuroendocrine tumor markers and enterochromaffin-like cell hyper/dysplasia in type 1 diabetes. Diabetes Care. 2004; 27(6): 1387–1393.
- Bizzaro N, Antico A, Villalta D. Autoimmunity and Gastric Cancer. Int J Mol Sci. 2018; 19(2).
