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Vol 70, No 4 (2019)
Review paper
Submitted: 2018-11-26
Accepted: 2018-12-10
Published online: 2019-08-14
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Surgical approach to differentiated thyroid cancers (DTC) in children [Specyfika leczenia chirurgicznego zróżnicowanych raków tarczycy (ZRT) u dzieci]

Agnieszka Czarniecka1, Grzegorz Woźniak1, Aleksandra Kropińska2, Barbara Jarząb2, Daria Handkiewicz-Junak2
DOI: 10.5603/EP.a2019.0033
·
Pubmed: 31489960
·
Endokrynol Pol 2019;70(4):357-366.
Affiliations
  1. The Oncological and Reconstructive Surgery Clinic, M. Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Poland
  2. Department of Nuclear Medicine and Endocrine Oncology, M. Sklodowska-Curie Institute — Oncology Centre, Gliwice, Poland

open access

Vol 70, No 4 (2019)
Reviews — Postgraduate Education
Submitted: 2018-11-26
Accepted: 2018-12-10
Published online: 2019-08-14

Abstract

Thyroid cancer in children is rare and accounts for 1–3% of all malignant tumours. Differentiated thyroid cancers (DTC) and particularly papillary thyroid carcinoma (PTC) (90% of cases) are the most prevalent. Surgery is the mainstay of treatment in patients with DTC. The current recommendations are based not on prospective randomised clinical trials, but on retrospective trials and expert opinions. Therefore, it is not easy to choose the optimal therapeutic strategy to obtain the best treatment and to avoid serious complications and adverse events. In children and adolescents, the clinical presentation, course, and prognosis are different from those seen in adults. Children are generally at low risk of death but at higher risk of long-term harm due to overly aggressive treatment. Therefore, optimisation of the therapeutic strategy is particularly important. The present paper provides a summary of the current guidelines on surgical management in thyroid tumours and DTC in children and adolescents. 

Abstract

Thyroid cancer in children is rare and accounts for 1–3% of all malignant tumours. Differentiated thyroid cancers (DTC) and particularly papillary thyroid carcinoma (PTC) (90% of cases) are the most prevalent. Surgery is the mainstay of treatment in patients with DTC. The current recommendations are based not on prospective randomised clinical trials, but on retrospective trials and expert opinions. Therefore, it is not easy to choose the optimal therapeutic strategy to obtain the best treatment and to avoid serious complications and adverse events. In children and adolescents, the clinical presentation, course, and prognosis are different from those seen in adults. Children are generally at low risk of death but at higher risk of long-term harm due to overly aggressive treatment. Therefore, optimisation of the therapeutic strategy is particularly important. The present paper provides a summary of the current guidelines on surgical management in thyroid tumours and DTC in children and adolescents. 

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Keywords

differentiated thyroid cancer; children, surgery

About this article
Title

Surgical approach to differentiated thyroid cancers (DTC) in children [Specyfika leczenia chirurgicznego zróżnicowanych raków tarczycy (ZRT) u dzieci]

Journal

Endokrynologia Polska

Issue

Vol 70, No 4 (2019)

Article type

Review paper

Pages

357-366

Published online

2019-08-14

Page views

1408

Article views/downloads

1010

DOI

10.5603/EP.a2019.0033

Pubmed

31489960

Bibliographic record

Endokrynol Pol 2019;70(4):357-366.

Keywords

differentiated thyroid cancer
children
surgery

Authors

Agnieszka Czarniecka
Grzegorz Woźniak
Aleksandra Kropińska
Barbara Jarząb
Daria Handkiewicz-Junak

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