Vol 1, No 5 (2012)
Research paper
Published online: 2013-01-07

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Analysis of the occurrence of cancers in patients with diabetes mellitus type 2

Dorota Łukasiewicz, Iwona Jakubowska, Magdalena Pędich-Czaban Pędich-Czaban
Diabetologia Kliniczna 2012;1(5):177-184.

Abstract

Background. The aim of this study was to evaluate
the incidence of cancer occurrence in patients with
type 2 diabetes staying under care of Regional
Diabetes Outpatient in Bialystok.


Material and methods. We retrospectively analyzed
the medical records of patients with type 2 diabetes,
identifying a patients diagnosed with cancer during
the treatment of type 2 diabetes. We analyzed factors
such as age, gender, family history and body weight
(expressed as BMI — body mass index), smoking. The
duration of diabetes, the medical treatment and
metabolic control were carefully evaluated. In
patients treated with insulin, insulin doses, average
number of units per kilogram of body weight per
day (units/kg/day) were analyzed.

Results. There are differences in the incidence of
various types of cancer in patients with diabetes
compared with the general population. In our study
group the most frequent were cancers of kidney,
colon, breast and uterus. In men with type 2 diabetes
cancer of the kidney and colon were most commonly
diagnosed, in female subgroup the most common
were breast cancer and colon cancer. Most of the
patients were obese patients.
Conclusions. In the study group of patients with type 2
diabetes, cancer was diagnosed in 5.9%. The most
common malignancies were renal cancer in men and
breast cancer in women. 80% of patients with type 2
diabetes who were diagnosed with cancer were
overweight or obese.

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