Vol 29, No 5 (2022)
Image in Cardiovascular Medicine
Published online: 2022-09-29

open access

Page views 4136
Article views/downloads 614
Get Citation

Connect on Social Media

Connect on Social Media

Acute myocardial injury as a sole presentation of COVID-19 in patient without cardiovascular risk factors

Dominika Filipiak-Strzecka1, Michał Plewka12, Ewa Szymczyk1, Karolina Frynas-Jończyk1, Konrad Szymczyk1, Piotr Lipiec1, Jarosław D. Kasprzak1
Pubmed: 36196658
Cardiol J 2022;29(5):878-879.

Abstract

Not available

covid-19

IMAGE IN CARDIOVASCULAR MEDICINE

Cardiology Journal

2022, Vol. 29, No. 5, 878–879

DOI: 10.5603/CJ.2022.0083

Copyright © 2022 Via Medica

ISSN 1897–5593

eISSN 1898018X

Acute myocardial injury as a sole presentation of COVID-19 in patient without cardiovascular risk factors

Dominika Filipiak-Strzecka1Michał Plewka12Ewa Szymczyk1Karolina Frynas-Jończyk1Konrad Szymczyk1Piotr Lipiec1Jarosław D. Kasprzak1
1Department and Chair of Cardiology, Medical University of Lodz, Bieganski Hospital, Lodz, Poland
2Department of Interventional Cardiology and Cardiac Arrhythmias, Medical University of Lodz, Poland
215748.png

Address for correspondence: Dominika Filipiak-Strzecka, PhD, Chair and Department of Cardiology, Medical University of Lodz, Bieganski Hospital, ul. Kniaziewicza 1/5, 91–347 Łódź, Poland, tel/fax: +48 42 2516216, e-mail: dominika.filipiak@gmail.com

Received: 9.02.2022 Accepted: 19.05.2022

This article is available in open access under Creative Common Attribution-Non-Commercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0) license, allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.

A previously healthy 49-year-old male without cardiovascular risk factors was admitted to the cardiology ward with severe resting chest pain. No fever, cough or dyspnea was reported. electrocardiography examination showed ST segment elevation in the inferior leads. His troponin-T level was increasing from 16 to 266 ng/L. Markers and NT-pro- -B-type natriuretic peptide levels were elevated. Urgent coronarography exposed no hemodynamically significant abnormalities (Fig. 1A, C). Persisting chest pain led to the angio-computed tomography (CT) and high resolution CT excluding pneumonia or acute aortic dissection. However, the patient tested positive for coronavirus disease 2019 (COVID-19) RT-PCR and was transferred to the COVID-19 cardiac ward. Echocardiography showed left ventricular (LV)-wall motion abnormalities within the inferolateral wall and septum, LV ejection fraction: 43% and LV global longitudinal strain: –14%. Five-day treatment with remdesivir was implemented. The initial diagnosis of myocarditis was proposed but magnetic resonance imaging (MRI) performed after 14 days showed subendocardial late gadolinium enhancement (50–75% wall thickness, locally transmural; Fig. 1E) in the middle and apical segments of inferolateral wall. Subendocardial high T2 signal intensity indicated myocardial edema (Fig. 1F, G). As MRI was strongly suggestive for ischemic lesion, coronarography was reassessed and an overlooked minor posterolateral branch thrombus with late phase contrast retention was detected. Thus, final diagnosis was COVID-19-related thrombotic coronary occlusion (Fig. 1B). After 15 days the patient was discharged in a good general condition. One-year follow-up echocardiography confirmed persisting small (< 1 segment) hypokinetic area with abnormal local strain and recovered global LV function (Fig. 1D). This report highlights difficult differential diagnosis of acute cardiac injury in COVID-19, in this case due to an unexpected intracoronary thrombosis in normal coronary arteries.

242132.png
Figure 1. A–C. Views from coronarography; A. Right coronary artery, early phase of contrast enhancement; B. Right coronary artery, late phase, contrast retention in a minor posterolateral branch marked with an arrow; C. Normal left coronary artery with recessive circumflex artery; D. Echocardiographic examination after one year, bullseye view showing small region of abnormal local strain located in the inferolateral wall; E–G. Cardiac magnetic resonance views; E. Subendocardial late gadolinium enhancement detected in the middle and apical segments of inferolateral wall (marked with an arrow); F, G. Subendocardial high T2 signal intensity indicated myocardial edema (arrows).

Conflict of interest: None declared