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Comprehensive appraisal of cardiac motion artefact in optical coherence tomography
, 34, 51, 2, 62, 5, 1, 5237
Affiliations- Med-X Research Institute, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China
- Cardiology Department, Campo de Gibraltar Health Trust, Algeciras (Cádiz), Spain
- Klinikum Frankfurt (Oder), Frankfurt (Oder), Germany
- Miguel Servet University Hospital, Zaragoza, Spain
- Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
- CardioCare Heart Center, Marbella, Spain
- DRK Klinikum Westend, Berlin, Germany
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Abstract
Background: The relation between cardiac motion artefact (CMA) in optical coherence tomography
(OCT) and the phases of cardiac cycle is unclear.
Methods: Optical coherence tomography pullbacks containing metallic stents were co-registered with
angiography and retrospectively analyzed. The beginning of three phases, namely ejection, rapid-inflow
and diastasis, was identified in angiography. Rotation, shortening, elongation and repetition were
qualitatively labelled as CMA artefacts. Platforms with coaxial longitudinal connectors (ML8 and
Magmaris) entered a quantitative sub-study, consisting of measuring the length of their connector at
the beginning of each phase.
Results: A total of 261 stents (127 patients) were analyzed, including 105 stents for quantitative
sub-study. CMA was detected in 61 (23.4%) stents: rotation in 6 (2.3%), shortening in 50 (19.2%),
elongation in 51 (19.5%) and repetition in 12 (4.6%). Shortening was always observed during ejection
phase, while elongation and repetition were always observed during rapid-inflow. Rotation occurred in
both ejection and rapid-inflow phases, while no artefact was reported during diastasis. Longitudinal
connectors measured in early ejection phase and in early rapid-inflow phase were shorter and longer,
respectively, than those measured in diastasis, irrespective of the presence of CMA in the qualitative
assessment.
Conclusions: Cardiac motion artefact is prevalent in OCT studies, but shortening and elongation of
vascular structures occur during early ejection and during early rapid-inflow, respectively, to a greater
or lesser extent in all cases. Diastasis is free of CMA and hence the period in which longitudinal measurements
can be more accurately quantified.
Abstract
Background: The relation between cardiac motion artefact (CMA) in optical coherence tomography
(OCT) and the phases of cardiac cycle is unclear.
Methods: Optical coherence tomography pullbacks containing metallic stents were co-registered with
angiography and retrospectively analyzed. The beginning of three phases, namely ejection, rapid-inflow
and diastasis, was identified in angiography. Rotation, shortening, elongation and repetition were
qualitatively labelled as CMA artefacts. Platforms with coaxial longitudinal connectors (ML8 and
Magmaris) entered a quantitative sub-study, consisting of measuring the length of their connector at
the beginning of each phase.
Results: A total of 261 stents (127 patients) were analyzed, including 105 stents for quantitative
sub-study. CMA was detected in 61 (23.4%) stents: rotation in 6 (2.3%), shortening in 50 (19.2%),
elongation in 51 (19.5%) and repetition in 12 (4.6%). Shortening was always observed during ejection
phase, while elongation and repetition were always observed during rapid-inflow. Rotation occurred in
both ejection and rapid-inflow phases, while no artefact was reported during diastasis. Longitudinal
connectors measured in early ejection phase and in early rapid-inflow phase were shorter and longer,
respectively, than those measured in diastasis, irrespective of the presence of CMA in the qualitative
assessment.
Conclusions: Cardiac motion artefact is prevalent in OCT studies, but shortening and elongation of
vascular structures occur during early ejection and during early rapid-inflow, respectively, to a greater
or lesser extent in all cases. Diastasis is free of CMA and hence the period in which longitudinal measurements
can be more accurately quantified.
Keywords
tomography, optical coherence, artefact, percutaneous coronary intervention, coronary heart disease, stents
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About this articleTitle
Comprehensive appraisal of cardiac motion artefact in optical coherence tomography
Journal
Issue
Article type
Original Article
Pages
543-555
Published online
2021-10-26
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2493
Article views/downloads
549
DOI
Pubmed
Bibliographic record
Cardiol J 2023;30(4):543-555.
Keywords
tomography
optical coherence
artefact
percutaneous coronary intervention
coronary heart disease
stents
Authors
Miao Chu
Carlos Cortés
Lili Liu
Miguel Ángel Martínez-Hervás-Alonso
Bernd Reisbeck
Ruiyan Zhang
Shengxian Tu
Juan Luis Gutiérrez-Chico
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