open access

Vol 27, No 6 (2020)
Study Protocol
Submitted: 2020-05-21
Accepted: 2020-10-13
Published online: 2020-10-26
Get Citation

Pomeranian atRial flOw reguLatOr iN conGestive hEart failuRe (PROLONGER): Study protocol

Łukasz Lewicki12, Katarzyna Kosmalska3, Sebastian Liedtke2, Maciej Karwowski2, Janusz Siebert1, Robert Sabiniewicz4, Jakub Kiedrzyn2, Adrian Kot2, Marek Szołkiewicz2
Pubmed: 33140394
Cardiol J 2020;27(6):879-883.
  1. University Center for Cardiology, Gdansk, Poland
  2. Department of Cardiology and Angiology, Kashubian Center for Heart and Vascular Diseases, Pomeranian Hospitals, Wejherowo, Poland
  3. Department of Cardiology, Pomeranian Hospitals, Gdynia, Poland
  4. Department of Pediatric Cardiology and Congenital Heart Disease, Medical University of Gdansk, Poland, Gdansk, Poland

open access

Vol 27, No 6 (2020)
Study protocol — Interventional cardiology
Submitted: 2020-05-21
Accepted: 2020-10-13
Published online: 2020-10-26


Not available


Not available
Get Citation
About this article

Pomeranian atRial flOw reguLatOr iN conGestive hEart failuRe (PROLONGER): Study protocol


Cardiology Journal


Vol 27, No 6 (2020)

Article type

Study Protocol



Published online


Page views


Article views/downloads






Bibliographic record

Cardiol J 2020;27(6):879-883.


Łukasz Lewicki
Katarzyna Kosmalska
Sebastian Liedtke
Maciej Karwowski
Janusz Siebert
Robert Sabiniewicz
Jakub Kiedrzyn
Adrian Kot
Marek Szołkiewicz

References (16)
  1. Mosterd A, Hoes AW. Clinical epidemiology of heart failure. Heart. 2007; 93(9): 1137–1146.
  2. Redfield MM, Jacobsen SJ, Burnett JC, et al. Burden of systolic and diastolic ventricular dysfunction in the community: appreciating the scope of the heart failure epidemic. JAMA. 2003; 289(2): 194–202.
  3. Ponikowski P, Voors A, Anker S, et al. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J. 2016; 37(27): 2129–2200.
  4. Lam CSP, Voors AA, de Boer RA, et al. Heart failure with preserved ejection fraction: from mechanisms to therapies. Eur Heart J. 2018; 39(30): 2780–2792.
  5. Borlaug BA, Paulus WJ. Heart failure with preserved ejection fraction: pathophysiology, diagnosis, and treatment. Eur Heart J. 2011; 32(6): 670–679.
  6. Shah SJ, Feldman T, Ricciardi MJ, et al. One-Year safety and clinical outcomes of a transcatheter interatrial shunt device for the treatment of heart failure with preserved ejection fraction in the reduce elevated left atrial pressure in patients with heart failure (REDUCE LAP-HF I) trial: a randomized clinical trial. JAMA Cardiol. 2018; 3(10): 968–977.
  7. Guimarães L, Bergeron S, Bernier M, et al. Interatrial shunt with the second-generation V-Wave system for patients with advanced chronic heart failure. EuroIntervention. 2020; 15(16): 1426–1428.
  8. Paitazoglou C, Özdemir R, Pfister R, et al. The AFR-PRELIEVE trial: a prospective, non-randomised, pilot study to assess the Atrial Flow Regulator (AFR) in heart failure patients with either preserved or reduced ejection fraction. EuroIntervention. 2019; 15(5): 403–410.
  9. Niu X, Zhang Q, Xiao D, et al. A retrospective study of hemodynamic changes in patients after off-pump coronary artery bypass graft surgery using impedance cardiography. Med Sci Monit. 2019; 25: 3454–3462.
  10. Louvaris Z, Spetsioti S, Andrianopoulos V, et al. Cardiac output measurement during exercise in COPD: A comparison of dye dilution and impedance cardiography. Clin Respir J. 2019; 13(4): 222–231.
  11. Małek ŁA, Mróz A, Czajkowska A, et al. Accuracy of impedance cardiography for hemodynamic assessment during rest and exercise in wheelchair rugby players. Res Q Exerc Sport. 2019; 90(3): 336–343.
  12. Kurpaska M, Krzesiński P, Gielerak G, et al. Exercise impedance cardiography reveals impaired hemodynamic responses to exercise in hypertensives with dyspnea. Hypertens Res. 2019; 42(2): 211–222.
  13. Woltjer HH, Bogaard HJ, de Vries P. The technique of impedance cardiography. Eur Heart J. 1997; 18(9): 1396–1403.
  14. Silver MA, Cianci P, Brennan S, et al. Evaluation of impedance cardiography as an alternative to pulmonary artery catheterization in critically ill patients. Congest Heart Fail. 2004; 10(2 Suppl 2): 17–21.
  15. Lewicki L, Fijalkowska M, Karwowski M, et al. The non-invasive evaluation of heart function in patients with an acute myocardial infarction: The role of impedance cardiography. Cardiol J. 2019 [Epub ahead of print].
  16. Lewicki Ł, Sabiniewicz R, Siebert J, et al. Atrial flow regulator as a novel therapy for patients with chronic heart failure. Cardiol J. 2020; 27(3): 309–311.


Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By VM Media Group sp. z o.o., Grupa Via Medica, ul. Świętokrzyska 73, 80–180 Gdańsk, Poland
tel.:+48 58 320 94 94, fax:+48 58 320 94 60, e-mail: