Vol 28, No 5 (2021)
Review Article
Published online: 2020-09-21

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Small vessel coronary artery disease: How small can we go with myocardial revascularization?

Maciej T. Wybraniec12, Paweł Bańka12, Tomasz Bochenek12, Tomasz Roleder3, Katarzyna Mizia-Stec12
Pubmed: 32986235
Cardiol J 2021;28(5):767-778.


The issue of small coronary artery atherosclerosis represents an intriguing aspect of coronary artery disease, which is related with higher rates of peri- and post-procedural complications and impaired long-term outcome. This problem is further complicated by the unclear definition of small coronary vessel. Recent randomized controlled trials have provided new data on possible novel interventional treatment of small coronary vessels with drug-coated balloons instead of traditional new-generation drug-eluting stent implantation. Also, the conservative management represents a therapeutic option in light of the results of the recent ISCHEMIA trial. The current article provides an overview of the most appropriate definition, interventional management, and prognosis of small coronary artery atherosclerosis.

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