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Research letter
Published online: 2020-10-27
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Perioperative D-dimer levels after transcatheter aortic valve replacement: Comparison of patients with and without anticoagulant therapy

Akihiro Tobe, Akihito Tanaka, Yoshiyuki Tokuda, Toshihiko Nishi, Yusuke Miki, Kenji Furusawa, Hideki Ishii, Akihiko Usui, Toyoaki Murohara
DOI: 10.5603/CJ.a2020.0143
·
Pubmed: 33140388

open access

Ahead of print
Research letter
Published online: 2020-10-27

Abstract

Not available

Abstract

Not available
Get Citation

Keywords

TAVR; D-dimer; anticoagulant therapy; leaflet thrombosis

About this article
Title

Perioperative D-dimer levels after transcatheter aortic valve replacement: Comparison of patients with and without anticoagulant therapy

Journal

Cardiology Journal

Issue

Ahead of print

Published online

2020-10-27

DOI

10.5603/CJ.a2020.0143

Pubmed

33140388

Keywords

TAVR
D-dimer
anticoagulant therapy
leaflet thrombosis

Authors

Akihiro Tobe
Akihito Tanaka
Yoshiyuki Tokuda
Toshihiko Nishi
Yusuke Miki
Kenji Furusawa
Hideki Ishii
Akihiko Usui
Toyoaki Murohara

References (8)
  1. Jose J, Sulimov DS, El-Mawardy M, et al. Clinical Bioprosthetic Heart Valve Thrombosis After Transcatheter Aortic Valve Replacement: Incidence, Characteristics, and Treatment Outcomes. JACC Cardiovasc Interv. 2017; 10(7): 686–697.
  2. Yanagisawa R, Hayashida K, Yamada Y, et al. Incidence, predictors, and mid-term outcomes of possible leaflet thrombosis after TAVR. JACC Cardiovasc Imaging. 2016 [Epub ahead of print].
  3. Olson JD. D-dimer: an overview of hemostasis and fibrinolysis, assays, and clinical applications. Adv Clin Chem. 2015; 69: 1–46.
  4. Chakravarty T, Søndergaard L, Friedman J, et al. Subclinical leaflet thrombosis in surgical and transcatheter bioprosthetic aortic valves: an observational study. Lancet. 2017; 389(10087): 2383–2392.
  5. Nijenhuis VJ, Brouwer J, Søndergaard L, et al. Antithrombotic therapy in patients undergoing transcatheter aortic valve implantation. Heart. 2019; 105(10): 742–748.
  6. Nagao T, Hunakubo H, Suzuki M, et al. Trends in physiological coagulation factors in Japanese patients receiving novel oral anticoagulants. J Arrhythm. 2017; 33(2): 117–121.
  7. Dangas GD, Tijssen JGP, Wöhrle J, et al. A controlled trial of rivaroxaban after transcatheter aortic-valve replacement. N Engl J Med. 2020; 382(2): 120–129.
  8. De Backer O, Dangas GD, Jilaihawi H, et al. Reduced leaflet motion after transcatheter aortic-valve replacement. N Engl J Med. 2020; 382(2): 130–139.

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