open access

Vol 29, No 1 (2022)
Original Article
Submitted: 2019-10-06
Accepted: 2020-02-17
Published online: 2020-03-11
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Success rate and safety of catheter ablation in preexcitation syndrome: A comparison between adult and pediatric patients

Radosław Pietrzak1, Magda Franke2, Monika Gawałko3, Piotr Lodziński3, Paweł Balsam3, Marcin Grabowski3, Bożena Werner1
·
Pubmed: 32207846
·
Cardiol J 2022;29(1):88-92.
Affiliations
  1. Department of Pediatric Cardiology and General Pediatrics, Medical University of Warsaw, Poland
  2. Student Scientific Circle, Department of Pediatric Cardiology and General Pediatrics, Medical University of Warsaw, Poland
  3. 1st Chair and Department of Cardiology, Medical University of Warsaw, Poland

open access

Vol 29, No 1 (2022)
Original articles — Clinical cardiology
Submitted: 2019-10-06
Accepted: 2020-02-17
Published online: 2020-03-11

Abstract

Background: In contrast to adults, in whom cardiac rhythm disorders are mainly conditioned by coronary artery disease, in children, arrhythmias are most often associated with inherited heart disorders. Catheter ablation (CA) has an important role in the management of cardiac arrhythmias, in adults and children. The aim of the study was to assess and compare the efficacy and safety of CA in children and adults with preexcitation syndrome.
Methods: The study population comprised 43 adults and 43 children diagnosed with a Wolff-Parkinson-White syndrome (WPW). The mean age of the study population was 41 ± 15 years for adults and 14 ± 2.5 years for children. In all patients, an electrophysiological study and CA were performed. Analysis with respect to the procedure duration, fluoroscopy exposure time, location of accessory pathways (AP), immediate success rate and complications were performed.
Results: Electrophysiological study revealed the most frequent presence of left-sided AP (56% in children and 70% in adults). The mean procedure duration was 96 ± 36 min and 106 ± 51 min in children and adults, respectively (p = NS). The mean fluoroscopy duration was 8.5 ± 4.3 min and 5.9 ± 5.8 min in children and adults, respectively p < 0.05. The CA procedure was successful in 40 out of 43 (93%) adults and in 36 out of 43 (83.7%) children (p = NS). In 2 (4%) children minor complications occurred.
Conclusions: Ablation in children and adults are equally effective with respect to short-term clinical
observation

Abstract

Background: In contrast to adults, in whom cardiac rhythm disorders are mainly conditioned by coronary artery disease, in children, arrhythmias are most often associated with inherited heart disorders. Catheter ablation (CA) has an important role in the management of cardiac arrhythmias, in adults and children. The aim of the study was to assess and compare the efficacy and safety of CA in children and adults with preexcitation syndrome.
Methods: The study population comprised 43 adults and 43 children diagnosed with a Wolff-Parkinson-White syndrome (WPW). The mean age of the study population was 41 ± 15 years for adults and 14 ± 2.5 years for children. In all patients, an electrophysiological study and CA were performed. Analysis with respect to the procedure duration, fluoroscopy exposure time, location of accessory pathways (AP), immediate success rate and complications were performed.
Results: Electrophysiological study revealed the most frequent presence of left-sided AP (56% in children and 70% in adults). The mean procedure duration was 96 ± 36 min and 106 ± 51 min in children and adults, respectively (p = NS). The mean fluoroscopy duration was 8.5 ± 4.3 min and 5.9 ± 5.8 min in children and adults, respectively p < 0.05. The CA procedure was successful in 40 out of 43 (93%) adults and in 36 out of 43 (83.7%) children (p = NS). In 2 (4%) children minor complications occurred.
Conclusions: Ablation in children and adults are equally effective with respect to short-term clinical
observation

Get Citation

Keywords

catheter ablation, preexcitation syndrome, accessory pathways, arrhythmia, children, adults

About this article
Title

Success rate and safety of catheter ablation in preexcitation syndrome: A comparison between adult and pediatric patients

Journal

Cardiology Journal

Issue

Vol 29, No 1 (2022)

Article type

Original Article

Pages

88-92

Published online

2020-03-11

Page views

6350

Article views/downloads

1221

DOI

10.5603/CJ.a2020.0030

Pubmed

32207846

Bibliographic record

Cardiol J 2022;29(1):88-92.

Keywords

catheter ablation
preexcitation syndrome
accessory pathways
arrhythmia
children
adults

Authors

Radosław Pietrzak
Magda Franke
Monika Gawałko
Piotr Lodziński
Paweł Balsam
Marcin Grabowski
Bożena Werner

References (18)
  1. Klitzner TS, Wetzel GT, Saxon LA, et al. Radiofrequency ablation. A new era in the treatment of pediatric arrhythmias. Am J Dis Child. 1993; 147(7): 769–771.
  2. Boersma L, García-Moran E, Mont L, et al. Accessory pathway localization by QRS polarity in children with Wolff-Parkinson-White syndrome. J Cardiovasc Electrophysiol. 2002; 13(12): 1222–1226.
  3. Ceresnak SR, Dubin AM, Kim JJ, et al. Success rates in pediatric WPW ablation are improved with 3-dimensional mapping systems compared with fluoroscopy alone: a multicenter study. J Cardiovasc Electrophysiol. 2015; 26(4): 412–416.
  4. Pruszkowska-Skrzep P, Pluta S, Lenarczyk A, et al. A comparison of the clinical course of preexcitation syndrome in children and adolescents and in adults Cardiol J. 2007; 14(4): 384–390.
  5. Hafez Mm, Abu-Elkheir Mm, Shokier M, et al. Radiofrequency catheter ablation in children with supraventricular tachycardias: intermediate term follow up results. Clin Med Insights Cardiol. 2012; 6: 7–16.
  6. Di Biase L, Walsh EP. (2018, August). Epidemiology, clinical manifestations, and diagnosis of the Wolff-Parkinson-White syndrome. Retrieved from. http://www.uptodate.com.
  7. Knight BP. Anatomy, pathophysiology, and localization of accessory pathways in the preexcitation syndrome. Retrieved from. http://www.uptodate.com.
  8. Van Hare GF, Javitz H, Carmelli D, et al. Pediatric Electrophysiology Society. Prospective assessment after pediatric cardiac ablation: demographics, medical profiles, and initial outcomes. J Cardiovasc Electrophysiol. 2004; 15(7): 759–770.
  9. Dubin AM, Jorgensen NW, Radbill AE, et al. What have we learned in the last 20 years? A comparison of a modern era pediatric and congenital catheter ablation registry to previous pediatric ablation registries. Heart Rhythm. 2019; 16(1): 57–63.
  10. Soongswang J, Bhuripanyo K, Raungratanaamporn O, et al. Radiofrequency catheter ablation in pediatrics: experience at Siriraj Hospital. J Med Assoc Thai. 2000; 83(11): 1340–1347.
  11. Lee PC, Hwang B, Chen SA, et al. Electrophysiologic characteristics and radiofrequency catheter ablation in children with Wolff-Parkinson-White syndrome. Pacing Clin Electrophysiol. 2006; 29(5): 490–495.
  12. Van Hare GF, Javitz H, Carmelli D, et al. Prospective assessment after pediatric cardiac ablation: demographics, medical profiles, and initial outcomes. J Cardiovasc Electrophysiol. 2004; 15(7): 759–770.
  13. Kugler JD, Danford DA, Houston KA, et al. Pediatric radiofrequency catheter ablation registry success, fluoroscopy time, and complication rate for supraventricular tachycardia: comparison of early and recent eras. J Cardiovasc Electrophysiol. 2002; 13(4): 336–341.
  14. Läer S, Elshoff JP, Meibohm B, et al. Development of a safe and effective pediatric dosing regimen for sotalol based on population pharmacokinetics and pharmacodynamics in children with supraventricular tachycardia. J Am Coll Cardiol. 2005; 46(7): 1322–1330.
  15. Núñez F, Ruiz-Granell R, Martínez-Costa C, et al. Safety and efficacy of flecainide in the treatment of symptomatic children with Wolff-Parkinson-White syndrome. Pediatr Cardiol. 2010; 31(8): 1162–1165.
  16. Perry JC, Garson A. Flecainide acetate for treatment of tachyarrhythmias in children: review of world literature on efficacy, safety, and dosing. Am Heart J. 1992; 124(6): 1614–1621.
  17. Melo S, Scanavacca M, Pisani C, et al. Ablação com RF de arritmia na infância: registro observacional em 125 crianças. Arquivos Brasileiros de Cardiologia. 2012; 98(6): 514–518.
  18. Cheng CH, Sanders GD, Hlatky MA, et al. Cost-effectiveness of radiofrequency ablation for supraventricular tachycardia. Ann Intern Med. 2000; 133(11): 864–876.

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