open access

Vol 28, No 4 (2021)
Original Article
Submitted: 2019-01-12
Accepted: 2019-02-14
Published online: 2019-03-08
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The effect of Cistus incanus herbal tea supplementation on oxidative stress markers and lipid profile in healthy adults

Agnieszka Kuchta1, Agnieszka Konopacka2, Krzysztof Waleron2, Agnieszka Viapiana3, Marek Wesołowski3, Kamil Dąbkowski1, Agnieszka Ćwiklińska1, Agnieszka Mickiewicz4, Anna Śledzińska5, Ewa Wieczorek1, Anna Gliwińska1, Barbara Kortas-Stempak1, Maciej Jankowski1
DOI: 10.5603/CJ.a2019.0028
·
Pubmed: 30912576
·
Cardiol J 2021;28(4):534-542.
Affiliations
  1. Department of Clinical Chemistry, Medical University of Gdansk, Poland
  2. Department of Pharmaceutical Microbiology, Medical University of Gdansk, Poland
  3. Department of Analytical Chemistry, Medical University of Gdansk, Poland
  4. 1st Department of Cardiology, Medical University of Gdansk, Poland
  5. Department of Therapeutic Drug Monitoring and Pharmacogenetics, Medical University of Gdansk, Poland

open access

Vol 28, No 4 (2021)
Original articles — Clinical cardiology
Submitted: 2019-01-12
Accepted: 2019-02-14
Published online: 2019-03-08

Abstract

Background: Oxidative stress and dyslipidemia play a critical role in the development of cardiovascular disease (CVD). Regular intake of polyphenol-rich diets is associated with a reduced risk of CVDs.
Methods: The present study was a pilot study with 24 healthy volunteers and was designed to determine if a 12-week administration of Cistus incanus herbal tea, containing phenolic acids and flavonoids, reduces cardiovascular risk factors including oxidative stress and dyslipidemia in healthy adults. Phenolic compounds profile and antibacterial activity of Cistus incanus infusion were also measured.
Results: Herbal infusion led to improvement in lipid profile by increase (D4%, p = 0.033) high-density lipoprotein cholesterol concentration and decrease triglyceride (D14%, p = 0.013) concentrations. In addition, the Cistus incanus diet was associated with decreased serum concentrations of malondialdehyde (D16%, p < 0.01) and advanced oxidation protein products (D18%, p < 0.001).
Conclusions: Cistus incanus administration decreases cardiovascular risk factors including oxidative stress and dyslipidemia and this action supports the idea of using Cistus incanus tea on a daily basis as an effective dietary component for prevention of atherosclerotic CVD.

Abstract

Background: Oxidative stress and dyslipidemia play a critical role in the development of cardiovascular disease (CVD). Regular intake of polyphenol-rich diets is associated with a reduced risk of CVDs.
Methods: The present study was a pilot study with 24 healthy volunteers and was designed to determine if a 12-week administration of Cistus incanus herbal tea, containing phenolic acids and flavonoids, reduces cardiovascular risk factors including oxidative stress and dyslipidemia in healthy adults. Phenolic compounds profile and antibacterial activity of Cistus incanus infusion were also measured.
Results: Herbal infusion led to improvement in lipid profile by increase (D4%, p = 0.033) high-density lipoprotein cholesterol concentration and decrease triglyceride (D14%, p = 0.013) concentrations. In addition, the Cistus incanus diet was associated with decreased serum concentrations of malondialdehyde (D16%, p < 0.01) and advanced oxidation protein products (D18%, p < 0.001).
Conclusions: Cistus incanus administration decreases cardiovascular risk factors including oxidative stress and dyslipidemia and this action supports the idea of using Cistus incanus tea on a daily basis as an effective dietary component for prevention of atherosclerotic CVD.

Get Citation

Keywords

Cistus incanus, lipid profile, oxidative stress markers

About this article
Title

The effect of Cistus incanus herbal tea supplementation on oxidative stress markers and lipid profile in healthy adults

Journal

Cardiology Journal

Issue

Vol 28, No 4 (2021)

Article type

Original Article

Pages

534-542

Published online

2019-03-08

Page views

5130

Article views/downloads

7762

DOI

10.5603/CJ.a2019.0028

Pubmed

30912576

Bibliographic record

Cardiol J 2021;28(4):534-542.

Keywords

Cistus incanus
lipid profile
oxidative stress markers

Authors

Agnieszka Kuchta
Agnieszka Konopacka
Krzysztof Waleron
Agnieszka Viapiana
Marek Wesołowski
Kamil Dąbkowski
Agnieszka Ćwiklińska
Agnieszka Mickiewicz
Anna Śledzińska
Ewa Wieczorek
Anna Gliwińska
Barbara Kortas-Stempak
Maciej Jankowski

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