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Improvement of left ventricular diastolic function and left heart morphology in young women with morbid obesity six months after bariatric surgery
Affiliations- Department of Internal Medicine and Cardiology, Medical University of Warsaw, Poland
- Department of Psychology, SWPS University of Social Sciences and Humanities, Poland
- Department of General Surgery and Transplantology, Medical University of Warsaw, Poland
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Abstract
Background: Obesity contributes to left ventricular (LV) diastolic dysfunction (LVDD) and may lead to diastolic heart failure. Weight loss (WL) after bariatric surgery (BS) may influence LV morphology and function. Using echocardiography, this study assessed the effect of WL on LV diastolic function (LVDF) and LV and left atrium (LA) morphology 6 months after BS in young women with morbid obesity.
Methods: Echocardiography was performed in 60 women with body mass index ≥ 40 kg/m², aged 37.1 ± ± 9.6 years prior to and 6 months after BS. In 38 patients, well-controlled arterial hypertension was present. Heart failure, coronary artery disease, atrial fibrillation and mitral stenosis were exclusion criteria. Parameters of LV and LA morphology were obtained. To evaluate LVDF, mitral peak early (E) and atrial (A) velocities, E-deceleration time (DcT), pulmonary vein S, D and A reversal velocities were measured. Peak early diastolic mitral annular velocities (E’) and E/E’ were assessed.
Results: Mean WL post BS was 35.7 kg (27%). A postoperative decrease in LV wall thickness, LV mass (mean 183.7 to 171.5 g, p = 0.001) and LA parameters (area, volume) were observed. LVDD was diagnosed in 3 patients prior to and in 2 of them subsequent to the procedure. An improvement in LVDF Doppler indices were noted: increased E/A, D and E’ lateral, and decreased S/D and lateral E/E’. None of the patients showed increased LV filling pressure. No significant correlations between hypertension and echo-parameters were demonstrated.
Conclusions: Six months after BS weight loss resulted in the improvement of LVDF and left heart morphology in morbidly obese women. (Cardiol J 2018; 25, 1: 97–105)
Abstract
Background: Obesity contributes to left ventricular (LV) diastolic dysfunction (LVDD) and may lead to diastolic heart failure. Weight loss (WL) after bariatric surgery (BS) may influence LV morphology and function. Using echocardiography, this study assessed the effect of WL on LV diastolic function (LVDF) and LV and left atrium (LA) morphology 6 months after BS in young women with morbid obesity.
Methods: Echocardiography was performed in 60 women with body mass index ≥ 40 kg/m², aged 37.1 ± ± 9.6 years prior to and 6 months after BS. In 38 patients, well-controlled arterial hypertension was present. Heart failure, coronary artery disease, atrial fibrillation and mitral stenosis were exclusion criteria. Parameters of LV and LA morphology were obtained. To evaluate LVDF, mitral peak early (E) and atrial (A) velocities, E-deceleration time (DcT), pulmonary vein S, D and A reversal velocities were measured. Peak early diastolic mitral annular velocities (E’) and E/E’ were assessed.
Results: Mean WL post BS was 35.7 kg (27%). A postoperative decrease in LV wall thickness, LV mass (mean 183.7 to 171.5 g, p = 0.001) and LA parameters (area, volume) were observed. LVDD was diagnosed in 3 patients prior to and in 2 of them subsequent to the procedure. An improvement in LVDF Doppler indices were noted: increased E/A, D and E’ lateral, and decreased S/D and lateral E/E’. None of the patients showed increased LV filling pressure. No significant correlations between hypertension and echo-parameters were demonstrated.
Conclusions: Six months after BS weight loss resulted in the improvement of LVDF and left heart morphology in morbidly obese women. (Cardiol J 2018; 25, 1: 97–105)
Keywords
morbid obesity, bariatric surgery, echocardiography, left ventricular diastolic function, left atrium
About this articleTitle
Improvement of left ventricular diastolic function and left heart morphology in young women with morbid obesity six months after bariatric surgery
Journal
Issue
Pages
97-105
Published online
2017-05-19
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2533
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2069
DOI
Pubmed
Bibliographic record
Cardiol J 2018;25(1):97-105.
Keywords
morbid obesity
bariatric surgery
echocardiography
left ventricular diastolic function
left atrium
Authors
Katarzyna Kurnicka
Justyna Domienik-Karłowicz
Barbara Lichodziejewska
Maksymilian Bielecki
Marta Kozłowska
Sylwia Goliszek
Olga Dzikowska-Diduch
Wojciech Lisik
Maciej Kosieradzki
Piotr Pruszczyk
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