open access

Vol 23, No 6 (2016)
BASIC SCIENCE AND EXPERIMENTALNTAL CARDIOLOGY - ORIGINAL ARTICLES
Published online: 2016-09-30
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In vitro assessment of six aspiration catheters using a distal protection filter

Tatsuhiro Fujimura, Takayuki Okamura, Miyuki Ando, Kousuke Uchida, Takashi Tone, Fumio Yonezawa, Masafumi Yano
DOI: 10.5603/CJ.a2016.0085
·
Pubmed: 27714725
·
Cardiol J 2016;23(6):667-672.

open access

Vol 23, No 6 (2016)
BASIC SCIENCE AND EXPERIMENTALNTAL CARDIOLOGY - ORIGINAL ARTICLES
Published online: 2016-09-30

Abstract

Background: We assessed performance of 6 aspiration catheters for distal embolization using a distal protection filter in an in vitro experiment. In acute myocardial infarction, a distal protection filter is used for lesions likely to induce a distal embolism. Which aspiration cathether is most effective when used with a distal protection filter remains still unclear.
Methods: A 0.5-cm3 bolus of gelatin as a model of stagnant pools of coronary plaque debris was captured in the distal protection filter and aspirated by 6 aspiration catheters. We measured and compared the length of the suspended embolus matter.
Results: Among the 6 catheters evaluated, the use of the Export Advance catheter (Medtronic) resulted in significantly shorter lengths of the suspended embolus matter compared to the use of the TVAC II (Nipro), Thrombuster III SL (Kaneka), and Rebirth Pro (Goodman) catheters (p < 0.01). The residual embolus matter in all cases had drained distally to the distal protection filter when the filter was retrieved.
Conclusions: The use of the Export Advance catheter showed better performance using a distal protection filter in this in vitro experiment, and its use might be more effective in preventing distal embolisms in combination with a distal protection filter.

Abstract

Background: We assessed performance of 6 aspiration catheters for distal embolization using a distal protection filter in an in vitro experiment. In acute myocardial infarction, a distal protection filter is used for lesions likely to induce a distal embolism. Which aspiration cathether is most effective when used with a distal protection filter remains still unclear.
Methods: A 0.5-cm3 bolus of gelatin as a model of stagnant pools of coronary plaque debris was captured in the distal protection filter and aspirated by 6 aspiration catheters. We measured and compared the length of the suspended embolus matter.
Results: Among the 6 catheters evaluated, the use of the Export Advance catheter (Medtronic) resulted in significantly shorter lengths of the suspended embolus matter compared to the use of the TVAC II (Nipro), Thrombuster III SL (Kaneka), and Rebirth Pro (Goodman) catheters (p < 0.01). The residual embolus matter in all cases had drained distally to the distal protection filter when the filter was retrieved.
Conclusions: The use of the Export Advance catheter showed better performance using a distal protection filter in this in vitro experiment, and its use might be more effective in preventing distal embolisms in combination with a distal protection filter.

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Keywords

percutaneous coronary intervention; distal embolization; acute myocardial infarction; aspiration catheters; distal protection device and filter no-reflow

Supplementary Files (1)
Aspiration movie. Attached movie file contains 3 different kinds of aspiration catheters.
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2MB
About this article
Title

In vitro assessment of six aspiration catheters using a distal protection filter

Journal

Cardiology Journal

Issue

Vol 23, No 6 (2016)

Pages

667-672

Published online

2016-09-30

DOI

10.5603/CJ.a2016.0085

Pubmed

27714725

Bibliographic record

Cardiol J 2016;23(6):667-672.

Keywords

percutaneous coronary intervention
distal embolization
acute myocardial infarction
aspiration catheters
distal protection device and filter no-reflow

Authors

Tatsuhiro Fujimura
Takayuki Okamura
Miyuki Ando
Kousuke Uchida
Takashi Tone
Fumio Yonezawa
Masafumi Yano

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