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Monocyte to high-density lipoprotein cholesterol ratio is predictive of in-hospital and five-year mortality in ST-segment elevation myocardial infarction
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Abstract
Background: We assessed the value of monocyte to high-density lipoprotein cholesterol ratio (MHR) in predicting in-hospital and 5-year mortality and major adverse cardiovascular events (MACE) in ST-segment elevation myocardial infarction (STEMI) patients.
Methods: A group of 1,598 patients were enrolled and divided into tertiles according to MHR values. The effects of different variables on clinical outcomes were assessed by Cox regression analysis.
Results: MHR was found as an independent predictor of in-hospital mortality (HR = 3.745, 95% CI 1.308–5.950), in-hospital MACE (HR 1.501, 95% CI 1.015–1.993, p = 0.022) and 5-year mortality (HR = 2.048, 95% CI 1.225–4.091, p = 0.014) and 5-year MACE (HR 1.285, 95% CI 1.064–1.552, p = 0.009).
Conclusions: MHR is an independent predictor of in-hospital and long term mortality and MACE in STEMI.
Abstract
Background: We assessed the value of monocyte to high-density lipoprotein cholesterol ratio (MHR) in predicting in-hospital and 5-year mortality and major adverse cardiovascular events (MACE) in ST-segment elevation myocardial infarction (STEMI) patients.
Methods: A group of 1,598 patients were enrolled and divided into tertiles according to MHR values. The effects of different variables on clinical outcomes were assessed by Cox regression analysis.
Results: MHR was found as an independent predictor of in-hospital mortality (HR = 3.745, 95% CI 1.308–5.950), in-hospital MACE (HR 1.501, 95% CI 1.015–1.993, p = 0.022) and 5-year mortality (HR = 2.048, 95% CI 1.225–4.091, p = 0.014) and 5-year MACE (HR 1.285, 95% CI 1.064–1.552, p = 0.009).
Conclusions: MHR is an independent predictor of in-hospital and long term mortality and MACE in STEMI.
Keywords
monocyte to high-density lipoprotein ratio, ST-segment elevation myocardial infarction, monocyte, high density lipoprotein cholesterol
About this articleTitle
Monocyte to high-density lipoprotein cholesterol ratio is predictive of in-hospital and five-year mortality in ST-segment elevation myocardial infarction
Journal
Issue
Pages
505-512
Published online
2016-06-10
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2152
Article views/downloads
2349
DOI
Pubmed
Bibliographic record
Cardiol J 2016;23(5):505-512.
Keywords
monocyte to high-density lipoprotein ratio
ST-segment elevation myocardial infarction
monocyte
high density lipoprotein cholesterol
Authors
Sadık Kadri Açıkgöz
Eser Açıkgöz
Barış Şensoy
Salih Topal
Sinan Aydoğdu
