open access

Vol 23, No 5 (2016)
CLINICAL CARDIOLOGY Original articles
Published online: 2016-06-10
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Monocyte to high-density lipoprotein cholesterol ratio is predictive of in-hospital and five-year mortality in ST-segment elevation myocardial infarction

Sadık Kadri Açıkgöz, Eser Açıkgöz, Barış Şensoy, Salih Topal, Sinan Aydoğdu
DOI: 10.5603/CJ.a2016.0026
·
Pubmed: 27296159
·
Cardiol J 2016;23(5):505-512.

open access

Vol 23, No 5 (2016)
CLINICAL CARDIOLOGY Original articles
Published online: 2016-06-10

Abstract

Background: We assessed the value of monocyte to high-density lipoprotein cholesterol ratio (MHR) in predicting in-hospital and 5-year mortality and major adverse cardiovascular events (MACE) in ST-segment elevation myocardial infarction (STEMI) patients.

Methods: A group of 1,598 patients were enrolled and divided into tertiles according to MHR values. The effects of different variables on clinical outcomes were assessed by Cox regression analysis.

Results: MHR was found as an independent predictor of in-hospital mortality (HR = 3.745, 95% CI 1.308–5.950), in-hospital MACE (HR 1.501, 95% CI 1.015–1.993, p = 0.022) and 5-year mortality (HR = 2.048, 95% CI 1.225–4.091, p = 0.014) and 5-year MACE (HR 1.285, 95% CI 1.064–1.552, p = 0.009).

Conclusions: MHR is an independent predictor of in-hospital and long term mortality and MACE in STEMI.

Abstract

Background: We assessed the value of monocyte to high-density lipoprotein cholesterol ratio (MHR) in predicting in-hospital and 5-year mortality and major adverse cardiovascular events (MACE) in ST-segment elevation myocardial infarction (STEMI) patients.

Methods: A group of 1,598 patients were enrolled and divided into tertiles according to MHR values. The effects of different variables on clinical outcomes were assessed by Cox regression analysis.

Results: MHR was found as an independent predictor of in-hospital mortality (HR = 3.745, 95% CI 1.308–5.950), in-hospital MACE (HR 1.501, 95% CI 1.015–1.993, p = 0.022) and 5-year mortality (HR = 2.048, 95% CI 1.225–4.091, p = 0.014) and 5-year MACE (HR 1.285, 95% CI 1.064–1.552, p = 0.009).

Conclusions: MHR is an independent predictor of in-hospital and long term mortality and MACE in STEMI.

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Keywords

monocyte to high-density lipoprotein ratio, ST-segment elevation myocardial infarction, monocyte, high density lipoprotein cholesterol

About this article
Title

Monocyte to high-density lipoprotein cholesterol ratio is predictive of in-hospital and five-year mortality in ST-segment elevation myocardial infarction

Journal

Cardiology Journal

Issue

Vol 23, No 5 (2016)

Pages

505-512

Published online

2016-06-10

DOI

10.5603/CJ.a2016.0026

Pubmed

27296159

Bibliographic record

Cardiol J 2016;23(5):505-512.

Keywords

monocyte to high-density lipoprotein ratio
ST-segment elevation myocardial infarction
monocyte
high density lipoprotein cholesterol

Authors

Sadık Kadri Açıkgöz
Eser Açıkgöz
Barış Şensoy
Salih Topal
Sinan Aydoğdu

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