open access

Vol 23, No 2 (2016)
PREVENTION - Original articles
Published online: 2016-01-07
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Impact of plant-based diet on lipid risk factors for atherosclerosis

Agnieszka Kuchta, Anna Lebiedzińska, Marcin Fijałkowski, Rafał Gałąska, Ewelina Kreft, Magdalena Totoń, Kuba Czaja, Anna Kozłowska, Agnieszka Ćwiklińska, Barbara Kortas-Stempak, Adrian Strzelecki, Anna Gliwińska, Kamil Dąbkowski, Maciej Jankowski
DOI: 10.5603/CJ.a2016.0002
·
Pubmed: 26779974
·
Cardiol J 2016;23(2):141-148.

open access

Vol 23, No 2 (2016)
PREVENTION - Original articles
Published online: 2016-01-07

Abstract

Background: The aim of the study was to investigate the effect of a vegan diet on the serum lipid profile with particular regard to the parameters characterizing the high-density lipoprotein (HDL) fractions in subjects without subclinical atherosclerosis, measured by carotid Doppler ultrasonography.

Methods and Results: Forty-two 23 to 38 year old subjects (21 omnivores and 21 vegans) participated in the study. Compared to the omnivores, the vegan subjects were characterized by lower parameters of lipid profile: total cholesterol (p < 0.001), low-density lipoprotein (LDL)-cholesterol (p < 0.001), non-HDL-cholesterol (p < 0.001), apolipoprotein B (apoB) (p < 0.001) and phospholipids (p < 0.01). Concentration of HDL-cholesterol was apparently similar between groups. Furthermore, the parameters which characterize HDL particles (con­centration of apolipoproteins AI [apoAI] and AII, HDL-phospholipids, LpAI fraction and pre-b1-HDL fraction) were not significantly different between omnivore and vegan subjects. The apoB/apoAI ratio in vegans was lower than in omnivores (p < 0.01). There was no difference between serum concentration of triacylglycerols between omnivores and vegans. The activity of paraoxonase-1 and 8-iso-prostaglandin F2a concentration were also not different between the study groups.

Conclusions: We suggest that a vegan diet may have a beneficial effect on serum lipid profile and cardiovascular protection, but it is not associated with changes in HDL composition.

Abstract

Background: The aim of the study was to investigate the effect of a vegan diet on the serum lipid profile with particular regard to the parameters characterizing the high-density lipoprotein (HDL) fractions in subjects without subclinical atherosclerosis, measured by carotid Doppler ultrasonography.

Methods and Results: Forty-two 23 to 38 year old subjects (21 omnivores and 21 vegans) participated in the study. Compared to the omnivores, the vegan subjects were characterized by lower parameters of lipid profile: total cholesterol (p < 0.001), low-density lipoprotein (LDL)-cholesterol (p < 0.001), non-HDL-cholesterol (p < 0.001), apolipoprotein B (apoB) (p < 0.001) and phospholipids (p < 0.01). Concentration of HDL-cholesterol was apparently similar between groups. Furthermore, the parameters which characterize HDL particles (con­centration of apolipoproteins AI [apoAI] and AII, HDL-phospholipids, LpAI fraction and pre-b1-HDL fraction) were not significantly different between omnivore and vegan subjects. The apoB/apoAI ratio in vegans was lower than in omnivores (p < 0.01). There was no difference between serum concentration of triacylglycerols between omnivores and vegans. The activity of paraoxonase-1 and 8-iso-prostaglandin F2a concentration were also not different between the study groups.

Conclusions: We suggest that a vegan diet may have a beneficial effect on serum lipid profile and cardiovascular protection, but it is not associated with changes in HDL composition.

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Keywords

atherosclerosis, plant-based diet, lipoproteins

About this article
Title

Impact of plant-based diet on lipid risk factors for atherosclerosis

Journal

Cardiology Journal

Issue

Vol 23, No 2 (2016)

Pages

141-148

Published online

2016-01-07

DOI

10.5603/CJ.a2016.0002

Pubmed

26779974

Bibliographic record

Cardiol J 2016;23(2):141-148.

Keywords

atherosclerosis
plant-based diet
lipoproteins

Authors

Agnieszka Kuchta
Anna Lebiedzińska
Marcin Fijałkowski
Rafał Gałąska
Ewelina Kreft
Magdalena Totoń
Kuba Czaja
Anna Kozłowska
Agnieszka Ćwiklińska
Barbara Kortas-Stempak
Adrian Strzelecki
Anna Gliwińska
Kamil Dąbkowski
Maciej Jankowski

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