open access

Vol 23, No 2 (2016)
ECHOCARDIOGRAPHY - Original articles
Published online: 2016-04-29
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Association between aortic stiffness and left ventricular function in inflammatory bowel disease

Abdullah Nabi Aslan, Cenk Sarı, Sevil Özer Sarı, Öykü Tayfur Yürekli, Serdal Baştuğ, Serkan Sivri, Osman Ersoy, Engin Bozkurt
DOI: 10.5603/CJ.a2016.0008
·
Pubmed: 26779973
·
Cardiol J 2016;23(2):202-210.

open access

Vol 23, No 2 (2016)
ECHOCARDIOGRAPHY - Original articles
Published online: 2016-04-29

Abstract

Background: Recent studies have reported an increased incidence of both aortic stiffness and left ventricular (LV) systolic and diastolic dysfunction in patients with inflammatory bowel disease (IBD). However, the association between aortic stiffness and the LV function has not been fully defined. We aimed to investigate the relationship between aortic stiffness and the LV function in IBD patients.

Methods and Results: Seventy-two patients with IBD (56 cases of ulcerative colitis and 16 cases of Crohn’s disease) and 50 healthy controls were consecutively enrolled in this study. The LV systolic and diastolic functions were assessed using conventional echocardiographic techniques, including tissue Doppler echocardiography. The degree of aortic strain and distensibility were calculated based on the aortic diameters measured on M-mode echocardiography at the level of 3 cm above the aortic valve and the blood pressure values obtained on sphygmomanometry. There were significant differences between the IBD and control group in the degree of aortic strain and distensibility. Significant differences were also observed between the patient and control groups in the parameters of the LV systolic and diastolic functions. Moreover, aortic stiffness was found to be associated with the LV function in the patient group.

Conclusions: There is a significant relationship between aortic stiffness and LV systolic and diastolic dysfunction in patients with IBD, based on the findings of this study. The parameters of aortic elasticity measured according to 2-dimensional echocardiographic methods can be beneficial for predicting early cardiovascular risk in cases of IBD. (

Abstract

Background: Recent studies have reported an increased incidence of both aortic stiffness and left ventricular (LV) systolic and diastolic dysfunction in patients with inflammatory bowel disease (IBD). However, the association between aortic stiffness and the LV function has not been fully defined. We aimed to investigate the relationship between aortic stiffness and the LV function in IBD patients.

Methods and Results: Seventy-two patients with IBD (56 cases of ulcerative colitis and 16 cases of Crohn’s disease) and 50 healthy controls were consecutively enrolled in this study. The LV systolic and diastolic functions were assessed using conventional echocardiographic techniques, including tissue Doppler echocardiography. The degree of aortic strain and distensibility were calculated based on the aortic diameters measured on M-mode echocardiography at the level of 3 cm above the aortic valve and the blood pressure values obtained on sphygmomanometry. There were significant differences between the IBD and control group in the degree of aortic strain and distensibility. Significant differences were also observed between the patient and control groups in the parameters of the LV systolic and diastolic functions. Moreover, aortic stiffness was found to be associated with the LV function in the patient group.

Conclusions: There is a significant relationship between aortic stiffness and LV systolic and diastolic dysfunction in patients with IBD, based on the findings of this study. The parameters of aortic elasticity measured according to 2-dimensional echocardiographic methods can be beneficial for predicting early cardiovascular risk in cases of IBD. (

Get Citation

Keywords

aortic stiffness, left ventricular function, inflammatory bowel disease, tissue Doppler echocardiography

About this article
Title

Association between aortic stiffness and left ventricular function in inflammatory bowel disease

Journal

Cardiology Journal

Issue

Vol 23, No 2 (2016)

Pages

202-210

Published online

2016-04-29

DOI

10.5603/CJ.a2016.0008

Pubmed

26779973

Bibliographic record

Cardiol J 2016;23(2):202-210.

Keywords

aortic stiffness
left ventricular function
inflammatory bowel disease
tissue Doppler echocardiography

Authors

Abdullah Nabi Aslan
Cenk Sarı
Sevil Özer Sarı
Öykü Tayfur Yürekli
Serdal Baştuğ
Serkan Sivri
Osman Ersoy
Engin Bozkurt

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