open access

Vol 23, No 2 (2016)
ECHOCARDIOGRAPHY - Original articles
Published online: 2016-04-29
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Four chamber right ventricular longitudinal strain versus right free wall longitudinal strain. Prognostic value in patients with left heart disease

Ana García-Martín, José-Luis Moya-Mur, Sonsoles Alejandra Carbonell-San Román, Alberto García-Lledó, Paula Navas-Tejedor, Alfonso Muriel, Daniel Rodríguez-Muñoz, Eduardo Casas-Rojo, Jose-Julio Jiménez-Nacher, Covadonga Fernández-Golfín, José-Luis Zamorano
DOI: 10.5603/CJ.a2015.0079
·
Pubmed: 26711464
·
Cardiol J 2016;23(2):189-194.

open access

Vol 23, No 2 (2016)
ECHOCARDIOGRAPHY - Original articles
Published online: 2016-04-29

Abstract

Background: There is no consensus on which right ventricle (RV) strain parameter should be used in the clinical practice: four chamber RV longitudinal strain (4CH RV-LS) or free wall longitudinal strain (FWLS). The aim of this study was to analyze which RV strain parameter better predicts prognosis in patients with left heart disease.

Methods: One hundred and three outpatients with several degrees of functional tricuspid regurgitation severity secondary to left heart disease were prospectively included. 4CH RV-LS and FWLS were assessed using speckle tracking. Left ventricular (LV) systolic function was determined using LV ejection fraction and RV systolic function using tricuspid annular plane systolic excursion (TAPSE). Patients were followed up for 23.1 ± 12.4 months for an endpoint of cardiac hospitalization due to heart failure.

Results: The cutoff value related to RV dysfunction (TAPSE < 17 mm) was lower, in absolute value, for 4CH RV-LS (4CH RV-LS = –17.3%; FWLS = –19.5%). There were 33 adverse events during the follow-up. Patients with 4CH RV-LS > –17.3% (log rank [LR] = 22.033; p < 0.001); FWLS > –19.5% (LR = 12.2; p < 0.001), TAPSE < 17 mm (LR = 17.4; p < 0.001) and LV systolic dysfunction (LR = 13.3; p < 0.001) had lower event-free survival (Kaplan Meier). In Cox multivariate analysis, 4CH RV-LS > –17.3% (hazard ratio [HR] = 3.593; p < 0.002), TAPSE < 17 (HR = 2.093; p < 0.055) and LV systolic dysfunction (HR = 2.087; p < 0,054) had prognostic value, whereas FWLS did not reach significance.

Conclusions: Although both 4CH RV-LS and FWLS have prognostic value, 4CH RV-LS is a better predictor of episodes of heart failure in patients with left heart disease, providing additional information to that obtained by TAPSE.

Abstract

Background: There is no consensus on which right ventricle (RV) strain parameter should be used in the clinical practice: four chamber RV longitudinal strain (4CH RV-LS) or free wall longitudinal strain (FWLS). The aim of this study was to analyze which RV strain parameter better predicts prognosis in patients with left heart disease.

Methods: One hundred and three outpatients with several degrees of functional tricuspid regurgitation severity secondary to left heart disease were prospectively included. 4CH RV-LS and FWLS were assessed using speckle tracking. Left ventricular (LV) systolic function was determined using LV ejection fraction and RV systolic function using tricuspid annular plane systolic excursion (TAPSE). Patients were followed up for 23.1 ± 12.4 months for an endpoint of cardiac hospitalization due to heart failure.

Results: The cutoff value related to RV dysfunction (TAPSE < 17 mm) was lower, in absolute value, for 4CH RV-LS (4CH RV-LS = –17.3%; FWLS = –19.5%). There were 33 adverse events during the follow-up. Patients with 4CH RV-LS > –17.3% (log rank [LR] = 22.033; p < 0.001); FWLS > –19.5% (LR = 12.2; p < 0.001), TAPSE < 17 mm (LR = 17.4; p < 0.001) and LV systolic dysfunction (LR = 13.3; p < 0.001) had lower event-free survival (Kaplan Meier). In Cox multivariate analysis, 4CH RV-LS > –17.3% (hazard ratio [HR] = 3.593; p < 0.002), TAPSE < 17 (HR = 2.093; p < 0.055) and LV systolic dysfunction (HR = 2.087; p < 0,054) had prognostic value, whereas FWLS did not reach significance.

Conclusions: Although both 4CH RV-LS and FWLS have prognostic value, 4CH RV-LS is a better predictor of episodes of heart failure in patients with left heart disease, providing additional information to that obtained by TAPSE.

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Keywords

right ventricle, right ventricular function, strain, echocardiography, heart failure

About this article
Title

Four chamber right ventricular longitudinal strain versus right free wall longitudinal strain. Prognostic value in patients with left heart disease

Journal

Cardiology Journal

Issue

Vol 23, No 2 (2016)

Pages

189-194

Published online

2016-04-29

DOI

10.5603/CJ.a2015.0079

Pubmed

26711464

Bibliographic record

Cardiol J 2016;23(2):189-194.

Keywords

right ventricle
right ventricular function
strain
echocardiography
heart failure

Authors

Ana García-Martín
José-Luis Moya-Mur
Sonsoles Alejandra Carbonell-San Román
Alberto García-Lledó
Paula Navas-Tejedor
Alfonso Muriel
Daniel Rodríguez-Muñoz
Eduardo Casas-Rojo
Jose-Julio Jiménez-Nacher
Covadonga Fernández-Golfín
José-Luis Zamorano

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