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Paravalvular leak after transcatheter aortic valve implantation (TAVI): Short-term results. Data from Polish national POL-TAVI registry
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Abstract
Background: The authors analyzed data from Polish national POL-TAVI registry in terms of paravalvular leak (PVL) occurrence after transcatheter aortic valve implantation (TAVI) and its impact on clinical outcomes.
Methods: A total of 331 patients with severe aortic stenosis underwent TAVI (Edwards Sapien, n = 141; CoreValve, n = 190). The grade of PVL and survival rate were assessed at 6-month follow-up.
Results: One hundred and eighty-one (54.7%) patients developed mild PVL, and 22 (6.6%) — moderate PVL after TAVI. No severe PVLs were observed. Occurrence of moderate PVL was device dependent and more frequent in the CoreValve group (p = 0.02). Larger CoreValve device used correlated with the grade of PVL (Spearman: r = 0.19; p = 0.01), but for Edwards Sapien devices this correlation was inverted (Spearman: r = –0.62; p = 0.01). Six-month mortality rate was not significant between patients with no or mild PVL compared to those with moderate PVL (p = 0.12).
Conclusions: The PVL occurrence remains a frequent problem after TAVI and is device dependent, more common with Edwards 23 mm valve and 31 mm CoreValve prosthesis
Abstract
Background: The authors analyzed data from Polish national POL-TAVI registry in terms of paravalvular leak (PVL) occurrence after transcatheter aortic valve implantation (TAVI) and its impact on clinical outcomes.
Methods: A total of 331 patients with severe aortic stenosis underwent TAVI (Edwards Sapien, n = 141; CoreValve, n = 190). The grade of PVL and survival rate were assessed at 6-month follow-up.
Results: One hundred and eighty-one (54.7%) patients developed mild PVL, and 22 (6.6%) — moderate PVL after TAVI. No severe PVLs were observed. Occurrence of moderate PVL was device dependent and more frequent in the CoreValve group (p = 0.02). Larger CoreValve device used correlated with the grade of PVL (Spearman: r = 0.19; p = 0.01), but for Edwards Sapien devices this correlation was inverted (Spearman: r = –0.62; p = 0.01). Six-month mortality rate was not significant between patients with no or mild PVL compared to those with moderate PVL (p = 0.12).
Conclusions: The PVL occurrence remains a frequent problem after TAVI and is device dependent, more common with Edwards 23 mm valve and 31 mm CoreValve prosthesis
Keywords
aortic stenosis, high-risk patients, TAVI, paravalvular leak
About this articleTitle
Paravalvular leak after transcatheter aortic valve implantation (TAVI): Short-term results. Data from Polish national POL-TAVI registry
Journal
Issue
Pages
163-168
Published online
2016-04-29
Page views
1897
Article views/downloads
1867
DOI
10.5603/CJ.a2015.0071
Pubmed
Bibliographic record
Cardiol J 2016;23(2):163-168.
Keywords
aortic stenosis
high-risk patients
TAVI
paravalvular leak
Authors
Paweł Kleczyński
Wojciech Zasada
Maciej Bagieński
Łukasz Rzeszutko
Danuta Sorysz
Robert Sobczyński
Jarosław Trębacz
Bogdan Kapelak
Marian Zembala
Dariusz Dudek
