open access

Vol 22, No 6 (2015)
Original articles
Published online: 2015-12-30
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Transaortic transcatheter aortic valve implantation: Results of the Polish arm of the ROUTE registry

Dariusz Jagielak, Peter Bramlage, Rafał Pawlaczyk, Maciej Brzeziński, Marcin Fijałkowski, Grzegorz Łaskawski, Dariusz Ciećwierz, Jan Rogowski, Radoslaw Kozaryn
DOI: 10.5603/CJ.a2015.0046
·
Pubmed: 26202653
·
Cardiol J 2015;22(6):651-656.

open access

Vol 22, No 6 (2015)
Original articles
Published online: 2015-12-30

Abstract

Background: Transaortic (TAo) transcatheter aortic valve implantation (TAVI) is an alter­native approach in patients considered to be at high risk for classical open surgery with poor peripheral vessel access. The purpose of this study was to determine the feasibility of using TAo access for TAVI procedures employing the Edwards SAPIEN transcatheter heart valve. The primary objective was to determine overall 30-day mortality.

Methods: A total of 32 patients with severe aortic valve stenosis underwent TAo-TAVI using Edwards SAPIEN bioprostheses. Postoperative results were collected according to the Registry of the Utilization Of the TAo-TAVI approach using the Edwards SAPIEN Valve (ROUTE) study protocol. Complications were assessed using Valve Academic Research Consortium- 2 (VARC-2) criteria.

Results: The mean age of the population was 80.9 ± 5.2 years, with 53.1% being female. All patients received either the SAPIEN XT or the SAPIEN 3 bioprosthesis (Edwards Lifesciences). Device success was achieved in 100% of cases. One (3.25%) patient subsequently suffered an aortic dissection and required ascending aorta replacement. Paravalvular leakage was absent or mild in 26 (81%) patients, and moderate in 6 (19%) patients. Other complications included permanent pacemaker implantation in 2 (6.5%), and transient post operative delirium in 2 (6.5%) patients. The total hospital stay was 6.7 ± 2.4 days. New York Heart Association class decreased significantly on follow-up. Thirty-day mortality rate was 2 (6.5%) patients.

Conclusions: Use of TAo access for TAVI procedures has a reasonable clinical outcome and is a safe alternative to the transfemoral and transapical approaches, especially for patients with high-risk peripheral vessel access.

Abstract

Background: Transaortic (TAo) transcatheter aortic valve implantation (TAVI) is an alter­native approach in patients considered to be at high risk for classical open surgery with poor peripheral vessel access. The purpose of this study was to determine the feasibility of using TAo access for TAVI procedures employing the Edwards SAPIEN transcatheter heart valve. The primary objective was to determine overall 30-day mortality.

Methods: A total of 32 patients with severe aortic valve stenosis underwent TAo-TAVI using Edwards SAPIEN bioprostheses. Postoperative results were collected according to the Registry of the Utilization Of the TAo-TAVI approach using the Edwards SAPIEN Valve (ROUTE) study protocol. Complications were assessed using Valve Academic Research Consortium- 2 (VARC-2) criteria.

Results: The mean age of the population was 80.9 ± 5.2 years, with 53.1% being female. All patients received either the SAPIEN XT or the SAPIEN 3 bioprosthesis (Edwards Lifesciences). Device success was achieved in 100% of cases. One (3.25%) patient subsequently suffered an aortic dissection and required ascending aorta replacement. Paravalvular leakage was absent or mild in 26 (81%) patients, and moderate in 6 (19%) patients. Other complications included permanent pacemaker implantation in 2 (6.5%), and transient post operative delirium in 2 (6.5%) patients. The total hospital stay was 6.7 ± 2.4 days. New York Heart Association class decreased significantly on follow-up. Thirty-day mortality rate was 2 (6.5%) patients.

Conclusions: Use of TAo access for TAVI procedures has a reasonable clinical outcome and is a safe alternative to the transfemoral and transapical approaches, especially for patients with high-risk peripheral vessel access.

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Keywords

aortic stenosis, transaortic approach, transcatheter aortic valve implantation, mini sternotomy, ROUTE registry

About this article
Title

Transaortic transcatheter aortic valve implantation: Results of the Polish arm of the ROUTE registry

Journal

Cardiology Journal

Issue

Vol 22, No 6 (2015)

Pages

651-656

Published online

2015-12-30

DOI

10.5603/CJ.a2015.0046

Pubmed

26202653

Bibliographic record

Cardiol J 2015;22(6):651-656.

Keywords

aortic stenosis
transaortic approach
transcatheter aortic valve implantation
mini sternotomy
ROUTE registry

Authors

Dariusz Jagielak
Peter Bramlage
Rafał Pawlaczyk
Maciej Brzeziński
Marcin Fijałkowski
Grzegorz Łaskawski
Dariusz Ciećwierz
Jan Rogowski
Radoslaw Kozaryn

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