open access

Vol 22, No 3 (2015)
Original articles
Published online: 2015-06-19
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Management of patients with valvular and non-valvular atrial fibrillation in Poland: Results from Reference Cardiology University Center

Paulina Łopatowska, Anna Tomaszuk-Kazberuk, Elżbieta Młodawska, Hanna Bachórzewska-Gajewska, Jolanta Małyszko, Sławomir Dobrzycki, Włodzimierz J. Musiał
DOI: 10.5603/CJ.a2014.0083
·
Pubmed: 25428729
·
Cardiol J 2015;22(3):296-305.

open access

Vol 22, No 3 (2015)
Original articles
Published online: 2015-06-19

Abstract

Background: Information on epidemiology of atrial fibrillation (AF) in Middle European Countries such as Poland is limited.

Methods: We studied 1,556 patients with AF. We focused on different types of AF in terms of clinical features and management.

Results: CHA2DS2-VASc score was 3.5 ± 1.7 and HAS-BLED score — 2.4 ± 1.1. In-hospital mortality was 2%. The CHA2DS2-VASc score was the highest in permanent AF (p < 0.001) and the HAS-BLED score was the highest in paroxysmal and permanent AF (p < 0.001). The CHA2DS2-VASc score ≥ 2 was found in the majority of non-valvular AF patients. Permanent AF was associated with the highest thromboembolic risk (p < 0.001). Valvular AF was more commonly observed in patients with permanent AF (p = 0.004). Seventy-one percent of pa­tients who had CHA2DS2-VASc > 2 received antithrombotic therapy. Acetylsalicylic acid alone was most common in paroxysmal AF (p < 0.001). Patients with valvular AF had more often permanent AF (p < 0.004). Valvular AF patients were more often prescribed antithrombotic therapy (p = 0.001). The in-hospital mortality did not differ between patients with valvular and non-valvular AF (p = 0.3). In multivariate logistic regression, odds of in-hospital death were higher for patients > 75 years old (OR = 6.26, p = 0.001, 95% CI 2.06–19.02) and with ejection fraction < 35% (OR = 5.25, p < 0.001, 95% CI 2.24–12.32).

Conclusions: Our population with AF have similar risk of stroke and bleeding as in Euro­pean registries. The need for anticoagulation in AF patients is well established in daily medical care in Poland similarly to Western Europe. Patients with valvular AF are more frequently prescribed antithrombotic therapy than patients with non-valvular AF. In-hospital mortality is relatively low in both valvular and non-valvular AF patients and is connected with old age and diminished ejection fraction.

Abstract

Background: Information on epidemiology of atrial fibrillation (AF) in Middle European Countries such as Poland is limited.

Methods: We studied 1,556 patients with AF. We focused on different types of AF in terms of clinical features and management.

Results: CHA2DS2-VASc score was 3.5 ± 1.7 and HAS-BLED score — 2.4 ± 1.1. In-hospital mortality was 2%. The CHA2DS2-VASc score was the highest in permanent AF (p < 0.001) and the HAS-BLED score was the highest in paroxysmal and permanent AF (p < 0.001). The CHA2DS2-VASc score ≥ 2 was found in the majority of non-valvular AF patients. Permanent AF was associated with the highest thromboembolic risk (p < 0.001). Valvular AF was more commonly observed in patients with permanent AF (p = 0.004). Seventy-one percent of pa­tients who had CHA2DS2-VASc > 2 received antithrombotic therapy. Acetylsalicylic acid alone was most common in paroxysmal AF (p < 0.001). Patients with valvular AF had more often permanent AF (p < 0.004). Valvular AF patients were more often prescribed antithrombotic therapy (p = 0.001). The in-hospital mortality did not differ between patients with valvular and non-valvular AF (p = 0.3). In multivariate logistic regression, odds of in-hospital death were higher for patients > 75 years old (OR = 6.26, p = 0.001, 95% CI 2.06–19.02) and with ejection fraction < 35% (OR = 5.25, p < 0.001, 95% CI 2.24–12.32).

Conclusions: Our population with AF have similar risk of stroke and bleeding as in Euro­pean registries. The need for anticoagulation in AF patients is well established in daily medical care in Poland similarly to Western Europe. Patients with valvular AF are more frequently prescribed antithrombotic therapy than patients with non-valvular AF. In-hospital mortality is relatively low in both valvular and non-valvular AF patients and is connected with old age and diminished ejection fraction.

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Keywords

valvular atrial fibrillation, non-valvular atrial fibrillation

About this article
Title

Management of patients with valvular and non-valvular atrial fibrillation in Poland: Results from Reference Cardiology University Center

Journal

Cardiology Journal

Issue

Vol 22, No 3 (2015)

Pages

296-305

Published online

2015-06-19

DOI

10.5603/CJ.a2014.0083

Pubmed

25428729

Bibliographic record

Cardiol J 2015;22(3):296-305.

Keywords

valvular atrial fibrillation
non-valvular atrial fibrillation

Authors

Paulina Łopatowska
Anna Tomaszuk-Kazberuk
Elżbieta Młodawska
Hanna Bachórzewska-Gajewska
Jolanta Małyszko
Sławomir Dobrzycki
Włodzimierz J. Musiał

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