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Feasibility and effect of para-right bundle branch pacing in patients with atrial fibrillation and complete atrioventricular block
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Abstract
Background: Chronic right ventricular apex (RVA) pacing can induce negative clinical effects. The aim of the present study was to compare RVA pacing with para-right bundle branch (para-RBB) pacing in terms of electrocardiogram (ECG) and echocardiographic (ECHO) features.
Methods: Forty-one consecutive persistent atrial fibrillation patients with an indication for permanent pacing treatment due to complete atrioventricular block were randomly assigned to receive a screw-in lead either in the RVA (n = 22) or at the para-RBB (n = 19). Para-RBB pacing leads were located according to the RBB potential recorded by electrophysiology catheter. ECG was recorded before and after implantation. All patients underwent the pacemaker programming at 1 day, 6 months, 12 months and 24 months after implantation. ECHO examination was performed during follow-up at 6, 12 and 24 months after implantation to assess the heart function and synchronism.
Results: There was no significant difference in pacing lead parameters between para-RBB pacing group and RVA pacing group. Compared with RVA pacing group, the para-RBB pacing group obtained a narrower QRS complex, more synchronic ventricular systole, and less negative effect on heart function (p < 0.05).
Conclusions: Para-RBB pacing has potential clinical benefits and may be a physiological pacing site.
Abstract
Background: Chronic right ventricular apex (RVA) pacing can induce negative clinical effects. The aim of the present study was to compare RVA pacing with para-right bundle branch (para-RBB) pacing in terms of electrocardiogram (ECG) and echocardiographic (ECHO) features.
Methods: Forty-one consecutive persistent atrial fibrillation patients with an indication for permanent pacing treatment due to complete atrioventricular block were randomly assigned to receive a screw-in lead either in the RVA (n = 22) or at the para-RBB (n = 19). Para-RBB pacing leads were located according to the RBB potential recorded by electrophysiology catheter. ECG was recorded before and after implantation. All patients underwent the pacemaker programming at 1 day, 6 months, 12 months and 24 months after implantation. ECHO examination was performed during follow-up at 6, 12 and 24 months after implantation to assess the heart function and synchronism.
Results: There was no significant difference in pacing lead parameters between para-RBB pacing group and RVA pacing group. Compared with RVA pacing group, the para-RBB pacing group obtained a narrower QRS complex, more synchronic ventricular systole, and less negative effect on heart function (p < 0.05).
Conclusions: Para-RBB pacing has potential clinical benefits and may be a physiological pacing site.
Keywords
cardiac pacing, atrioventricular block, atrial fibrillation, right bundle branch
About this articleTitle
Feasibility and effect of para-right bundle branch pacing in patients with atrial fibrillation and complete atrioventricular block
Journal
Issue
Pages
233-240
Published online
2015-06-19
Page views
1618
Article views/downloads
1858
DOI
10.5603/CJ.a2014.0060
Pubmed
Bibliographic record
Cardiol J 2015;22(3):233-240.
Keywords
cardiac pacing
atrioventricular block
atrial fibrillation
right bundle branch
Authors
You-You Du
Rui Yao
Qing-Hua Chen
Luo-Sha Zhao
Ling Li
