open access

Vol 22, No 2 (2015)
Original articles
Published online: 2015-04-28
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Left atrial appendage closure with the Amplatzer™ Cardiac Plug: Rationale for a higher degree of device oversizing at implantation

Joerg Neuzner, Thomas Dietze, Robert Paliege, Michael Möller, Giovanni Saeed, Rainer Gradaus
DOI: 10.5603/CJ.a2014.0063
·
Pubmed: 25299502
·
Cardiol J 2015;22(2):201-205.

open access

Vol 22, No 2 (2015)
Original articles
Published online: 2015-04-28

Abstract

Background: In left atrial appendage (LAA) closure, the correct sizing of the implantable devices is crucial. Data on the time-dependent changes in the shape and positioning of LAA occlusion devices are missing. We analyzed the results of 33 consecutive patients after implantation of an Amplatzer™ Cardiac Plug (ACP) LAA closure device to get more information on the optimal device sizing during implantation.

Methods and results: Thirty-three consecutive patients were enrolled in this observational study. ACP implantation was guided by fluoroscopy and three dimensional transesophageal echocardiography (3-D TEE). Device sizing was based on the largest measured diameter of the intended landing zone adding 2–4 mm of device oversizing. Fluoroscopies were performed at 1 day after, and after 3 months, control 3-D TEE was performed 3 months after implantation. The stability of device positioning and shape was matched with the results of 3-D TEE. Patients’ mean age was 70.2 ± 8 years; mean CHA2DS2VASc score was 3.8 ± 1.1. According to the manufacture’s classification, the post-implant degree of compression of the device-lobe was classified in three categories 1) undercompression “square-like shape” (1 patient); 2) op­timal compression “tire-like shape” (20 patients), 3) overcompression “strawberry-like shape” (12 patients). Changes in the degree of device compression by more than one classification class occurred in 18/33 of our patients. A complete loss of device compression (“square-like shape”) was observed in 9 patients. Despite the changes in device compression, a complete closure of the LAA was achieved in 32/33 patients.

Conclusions: There is a temporal change in shape and positioning of the ACP within 3 months after implantation. A late decompression of the ACP lobe was observed in 61% of our patients, leading to a complete loss in device compression in 27%. This observation may be the rationale for a higher degree of ACP oversizing during implantation.

Abstract

Background: In left atrial appendage (LAA) closure, the correct sizing of the implantable devices is crucial. Data on the time-dependent changes in the shape and positioning of LAA occlusion devices are missing. We analyzed the results of 33 consecutive patients after implantation of an Amplatzer™ Cardiac Plug (ACP) LAA closure device to get more information on the optimal device sizing during implantation.

Methods and results: Thirty-three consecutive patients were enrolled in this observational study. ACP implantation was guided by fluoroscopy and three dimensional transesophageal echocardiography (3-D TEE). Device sizing was based on the largest measured diameter of the intended landing zone adding 2–4 mm of device oversizing. Fluoroscopies were performed at 1 day after, and after 3 months, control 3-D TEE was performed 3 months after implantation. The stability of device positioning and shape was matched with the results of 3-D TEE. Patients’ mean age was 70.2 ± 8 years; mean CHA2DS2VASc score was 3.8 ± 1.1. According to the manufacture’s classification, the post-implant degree of compression of the device-lobe was classified in three categories 1) undercompression “square-like shape” (1 patient); 2) op­timal compression “tire-like shape” (20 patients), 3) overcompression “strawberry-like shape” (12 patients). Changes in the degree of device compression by more than one classification class occurred in 18/33 of our patients. A complete loss of device compression (“square-like shape”) was observed in 9 patients. Despite the changes in device compression, a complete closure of the LAA was achieved in 32/33 patients.

Conclusions: There is a temporal change in shape and positioning of the ACP within 3 months after implantation. A late decompression of the ACP lobe was observed in 61% of our patients, leading to a complete loss in device compression in 27%. This observation may be the rationale for a higher degree of ACP oversizing during implantation.

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Keywords

left atrial appendage occlusion, Amplatzer™ Cardiac Plug, device sizing, fluoroscopy

About this article
Title

Left atrial appendage closure with the Amplatzer™ Cardiac Plug: Rationale for a higher degree of device oversizing at implantation

Journal

Cardiology Journal

Issue

Vol 22, No 2 (2015)

Pages

201-205

Published online

2015-04-28

DOI

10.5603/CJ.a2014.0063

Pubmed

25299502

Bibliographic record

Cardiol J 2015;22(2):201-205.

Keywords

left atrial appendage occlusion
Amplatzer™ Cardiac Plug
device sizing
fluoroscopy

Authors

Joerg Neuzner
Thomas Dietze
Robert Paliege
Michael Möller
Giovanni Saeed
Rainer Gradaus

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