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open access

Vol 20, No 6 (2013)
Review Article
Submitted: 2013-12-11
Accepted: 2013-12-11
Published online: 2013-12-11
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Autoimmune diseases, their pharmacological treatment and the cardiovascular system

Marta Jastrzębska, Michael E. Czok, Przemysław Guzik
DOI: 10.5603/CJ.2013.0156
·
Cardiol J 2013;20(6):569-576.

open access

Vol 20, No 6 (2013)
Review articles
Submitted: 2013-12-11
Accepted: 2013-12-11
Published online: 2013-12-11

Abstract

Cardiovascular system involvement is a frequent complication of autoimmune diseases (AD) such as systemic lupus erythematosus, scleroderma, rheumatoid arthritis, spondyloarthropaties or psoriatic arthritis. The most common forms of such involvement are pericarditis, myocarditis, accelerated atherosclerosis resulting in myocardial infarction or stroke, arrhythmias, conduction abnormalities or congestive heart failure. Some of these manifestations may be dramatic in their course and ultimately fatal. The treatment of AD may further affect the cardiovascular system and result in a lower quality of life, higher mortality and increased cost of healthcare. The aim of this review is to discuss possible cardiac complications of various AD and the related treatment of these diseases.

Abstract

Cardiovascular system involvement is a frequent complication of autoimmune diseases (AD) such as systemic lupus erythematosus, scleroderma, rheumatoid arthritis, spondyloarthropaties or psoriatic arthritis. The most common forms of such involvement are pericarditis, myocarditis, accelerated atherosclerosis resulting in myocardial infarction or stroke, arrhythmias, conduction abnormalities or congestive heart failure. Some of these manifestations may be dramatic in their course and ultimately fatal. The treatment of AD may further affect the cardiovascular system and result in a lower quality of life, higher mortality and increased cost of healthcare. The aim of this review is to discuss possible cardiac complications of various AD and the related treatment of these diseases.

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Keywords

cardiovascular complications, autoimmune diseases, heart failure, adverse drug effects

About this article
Title

Autoimmune diseases, their pharmacological treatment and the cardiovascular system

Journal

Cardiology Journal

Issue

Vol 20, No 6 (2013)

Article type

Review Article

Pages

569-576

Published online

2013-12-11

Page views

4226

Article views/downloads

5221

DOI

10.5603/CJ.2013.0156

Bibliographic record

Cardiol J 2013;20(6):569-576.

Keywords

cardiovascular complications
autoimmune diseases
heart failure
adverse drug effects

Authors

Marta Jastrzębska
Michael E. Czok
Przemysław Guzik

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