open access

Vol 20, No 4 (2013)
Review paper
Get Citation

Transfusion-related acute lung injury: A dangerous and underdiagnosed noncardiogenic pulmonary edema

Krzysztof Jaworski, Krystyna Maślanka, Dariusz A. Kosior
DOI: 10.5603/CJ.2013.0091
·
Cardiol J 2013;20(4):337-344.

open access

Vol 20, No 4 (2013)
Review articles

Abstract

Transfusion-related acute lung injury (TRALI) is one of the leading causes of death associated
with transfusion of blood and blood components. The understanding of the etiology and
pathophysiology of this syndrome has much improved during the last decades, nevertheless
numerous issues are still unresolved and symptomatic treatment remains the cornerstone of
medical management. Consequently more attention is directed at primary as well as secondary
prevention. The awareness of the problem within the medical society is still unsatisfactory
which results in a high number of unrecognized cases or of inaccurate diagnoses one of which
is cardiogenic pulmonary edema. The aim of this review is to make the TRALI syndrome more
familiar to clinicians and to emphasize how signifi cant proper medical management is both for
the patients presenting TRALI symptoms as well as for future recipients of blood components.

Abstract

Transfusion-related acute lung injury (TRALI) is one of the leading causes of death associated
with transfusion of blood and blood components. The understanding of the etiology and
pathophysiology of this syndrome has much improved during the last decades, nevertheless
numerous issues are still unresolved and symptomatic treatment remains the cornerstone of
medical management. Consequently more attention is directed at primary as well as secondary
prevention. The awareness of the problem within the medical society is still unsatisfactory
which results in a high number of unrecognized cases or of inaccurate diagnoses one of which
is cardiogenic pulmonary edema. The aim of this review is to make the TRALI syndrome more
familiar to clinicians and to emphasize how signifi cant proper medical management is both for
the patients presenting TRALI symptoms as well as for future recipients of blood components.
Get Citation

Keywords

transfusion, pulmonary edema, leukocyte antibodies, respiratory distress

About this article
Title

Transfusion-related acute lung injury: A dangerous and underdiagnosed noncardiogenic pulmonary edema

Journal

Cardiology Journal

Issue

Vol 20, No 4 (2013)

Article type

Review paper

Pages

337-344

DOI

10.5603/CJ.2013.0091

Bibliographic record

Cardiol J 2013;20(4):337-344.

Keywords

transfusion
pulmonary edema
leukocyte antibodies
respiratory distress

Authors

Krzysztof Jaworski
Krystyna Maślanka
Dariusz A. Kosior

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