open access
Transfusion-related acute lung injury: A dangerous and underdiagnosed noncardiogenic pulmonary edema
open access
Abstract
with transfusion of blood and blood components. The understanding of the etiology and
pathophysiology of this syndrome has much improved during the last decades, nevertheless
numerous issues are still unresolved and symptomatic treatment remains the cornerstone of
medical management. Consequently more attention is directed at primary as well as secondary
prevention. The awareness of the problem within the medical society is still unsatisfactory
which results in a high number of unrecognized cases or of inaccurate diagnoses one of which
is cardiogenic pulmonary edema. The aim of this review is to make the TRALI syndrome more
familiar to clinicians and to emphasize how signifi cant proper medical management is both for
the patients presenting TRALI symptoms as well as for future recipients of blood components.
Abstract
with transfusion of blood and blood components. The understanding of the etiology and
pathophysiology of this syndrome has much improved during the last decades, nevertheless
numerous issues are still unresolved and symptomatic treatment remains the cornerstone of
medical management. Consequently more attention is directed at primary as well as secondary
prevention. The awareness of the problem within the medical society is still unsatisfactory
which results in a high number of unrecognized cases or of inaccurate diagnoses one of which
is cardiogenic pulmonary edema. The aim of this review is to make the TRALI syndrome more
familiar to clinicians and to emphasize how signifi cant proper medical management is both for
the patients presenting TRALI symptoms as well as for future recipients of blood components.
Keywords
transfusion, pulmonary edema, leukocyte antibodies, respiratory distress
About this articleTitle
Transfusion-related acute lung injury: A dangerous and underdiagnosed noncardiogenic pulmonary edema
Journal
Issue
Article type
Review Article
Pages
337-344
Published online
2013-07-26
Page views
3497
Article views/downloads
4602
DOI
10.5603/CJ.2013.0091
Bibliographic record
Cardiol J 2013;20(4):337-344.
Keywords
transfusion
pulmonary edema
leukocyte antibodies
respiratory distress
Authors
Krzysztof Jaworski
Krystyna Maślanka
Dariusz A. Kosior
