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Predictors of mortality in patients with prosthetic valve infective endocarditis: A nation-wide multicenter study
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Abstract
Background: Our aim was to investigate the clinical and prognostic features of the patients with prosthetic valve endocarditis (PVE) in a multicenter nation-wide study.
Methods: The present nation-wide study consisted of 75 consecutive patients with PVE treatedat 13 major hospitals in Turkey from 2005 to 2012.
Results: The patients who died during follow-up were significantly older than the survivors and had higher C-reactive protein (CRP), creatinine, poor NYHA functional class and large vegetations. High creatinine level (odds ratio [OR] 2.6, 95% confidence interval [CI] 1.14–6.13), poor functional status (OR 24.5; 95% CI 3.1–196.5) and high CRP (OR 1.02; 95% CI1.00–1.03) measured on admission were independent risk associates for in-hospital mortality.
Conclusions: High creatinine level, poor functional status and high CRP measured on admission were independent risk associates for in-hospital mortality, whereas a NYHA class ofIII/IV and high CRP reflected independent risk for stroke/mortality end point.
Abstract
Background: Our aim was to investigate the clinical and prognostic features of the patients with prosthetic valve endocarditis (PVE) in a multicenter nation-wide study.
Methods: The present nation-wide study consisted of 75 consecutive patients with PVE treatedat 13 major hospitals in Turkey from 2005 to 2012.
Results: The patients who died during follow-up were significantly older than the survivors and had higher C-reactive protein (CRP), creatinine, poor NYHA functional class and large vegetations. High creatinine level (odds ratio [OR] 2.6, 95% confidence interval [CI] 1.14–6.13), poor functional status (OR 24.5; 95% CI 3.1–196.5) and high CRP (OR 1.02; 95% CI1.00–1.03) measured on admission were independent risk associates for in-hospital mortality.
Conclusions: High creatinine level, poor functional status and high CRP measured on admission were independent risk associates for in-hospital mortality, whereas a NYHA class ofIII/IV and high CRP reflected independent risk for stroke/mortality end point.
Keywords
infective endocarditis, mortality, prognostic factors
About this articleTitle
Predictors of mortality in patients with prosthetic valve infective endocarditis: A nation-wide multicenter study
Journal
Issue
Pages
323-328
Published online
2013-06-01
Page views
2516
Article views/downloads
2595
DOI
10.5603/CJ.2013.0079
Bibliographic record
Cardiol J 2013;20(3):323-328.
Keywords
infective endocarditis
mortality
prognostic factors
Authors
Mehmet Ali Elbey
Mehmet Emin Kalkan
Serkan Akdag
Kerem Ozbek
Nihan Kahya Eren
Sinan Demirtas
Mehmet Ata Akil
Selim Topcu
Mustafa Oylumlu
Zihni Bilik
Murat Yuksel
