Vol 20, No 3 (2013)
Original articles
Published online: 2013-06-01

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Predictors of mortality in patients with prosthetic valve infective endocarditis: A nation-wide multicenter study

Mehmet Ali Elbey, Mehmet Emin Kalkan, Serkan Akdag, Kerem Ozbek, Nihan Kahya Eren, Sinan Demirtas, Mehmet Ata Akil, Selim Topcu, Mustafa Oylumlu, Zihni Bilik, Murat Yuksel
DOI: 10.5603/CJ.2013.0079
Cardiol J 2013;20(3):323-328.

Abstract

Background: Our aim was to investigate the clinical and prognostic features of the patients with prosthetic valve endocarditis (PVE) in a multicenter nation-wide study.

Methods: The present nation-wide study consisted of 75 consecutive patients with PVE treatedat 13 major hospitals in Turkey from 2005 to 2012.

Results: The patients who died during follow-up were significantly older than the survivors and had higher C-reactive protein (CRP), creatinine, poor NYHA functional class and large vegetations. High creatinine level (odds ratio [OR] 2.6, 95% confidence interval [CI] 1.14–6.13), poor functional status (OR 24.5; 95% CI 3.1–196.5) and high CRP (OR 1.02; 95% CI1.00–1.03) measured on admission were independent risk associates for in-hospital mortality.

Conclusions: High creatinine level, poor functional status and high CRP measured on admission were independent risk associates for in-hospital mortality, whereas a NYHA class ofIII/IV and high CRP reflected independent risk for stroke/mortality end point.