open access

Vol 20, No 3 (2013)
Original articles
Published online: 2013-06-01
Get Citation

Predictors of mortality in patients with prosthetic valve infective endocarditis: A nation-wide multicenter study

Mehmet Ali Elbey, Mehmet Emin Kalkan, Serkan Akdag, Kerem Ozbek, Nihan Kahya Eren, Sinan Demirtas, Mehmet Ata Akil, Selim Topcu, Mustafa Oylumlu, Zihni Bilik, Murat Yuksel
DOI: 10.5603/CJ.2013.0079
·
Cardiol J 2013;20(3):323-328.

open access

Vol 20, No 3 (2013)
Original articles
Published online: 2013-06-01

Abstract

Background: Our aim was to investigate the clinical and prognostic features of the patients with prosthetic valve endocarditis (PVE) in a multicenter nation-wide study.

Methods: The present nation-wide study consisted of 75 consecutive patients with PVE treatedat 13 major hospitals in Turkey from 2005 to 2012.

Results: The patients who died during follow-up were significantly older than the survivors and had higher C-reactive protein (CRP), creatinine, poor NYHA functional class and large vegetations. High creatinine level (odds ratio [OR] 2.6, 95% confidence interval [CI] 1.14–6.13), poor functional status (OR 24.5; 95% CI 3.1–196.5) and high CRP (OR 1.02; 95% CI1.00–1.03) measured on admission were independent risk associates for in-hospital mortality.

Conclusions: High creatinine level, poor functional status and high CRP measured on admission were independent risk associates for in-hospital mortality, whereas a NYHA class ofIII/IV and high CRP reflected independent risk for stroke/mortality end point.

Abstract

Background: Our aim was to investigate the clinical and prognostic features of the patients with prosthetic valve endocarditis (PVE) in a multicenter nation-wide study.

Methods: The present nation-wide study consisted of 75 consecutive patients with PVE treatedat 13 major hospitals in Turkey from 2005 to 2012.

Results: The patients who died during follow-up were significantly older than the survivors and had higher C-reactive protein (CRP), creatinine, poor NYHA functional class and large vegetations. High creatinine level (odds ratio [OR] 2.6, 95% confidence interval [CI] 1.14–6.13), poor functional status (OR 24.5; 95% CI 3.1–196.5) and high CRP (OR 1.02; 95% CI1.00–1.03) measured on admission were independent risk associates for in-hospital mortality.

Conclusions: High creatinine level, poor functional status and high CRP measured on admission were independent risk associates for in-hospital mortality, whereas a NYHA class ofIII/IV and high CRP reflected independent risk for stroke/mortality end point.

Get Citation

Keywords

infective endocarditis, mortality, prognostic factors

About this article
Title

Predictors of mortality in patients with prosthetic valve infective endocarditis: A nation-wide multicenter study

Journal

Cardiology Journal

Issue

Vol 20, No 3 (2013)

Pages

323-328

Published online

2013-06-01

DOI

10.5603/CJ.2013.0079

Bibliographic record

Cardiol J 2013;20(3):323-328.

Keywords

infective endocarditis
mortality
prognostic factors

Authors

Mehmet Ali Elbey
Mehmet Emin Kalkan
Serkan Akdag
Kerem Ozbek
Nihan Kahya Eren
Sinan Demirtas
Mehmet Ata Akil
Selim Topcu
Mustafa Oylumlu
Zihni Bilik
Murat Yuksel

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk, Poland
tel.:+48 58 320 94 94, fax:+48 58 320 94 60, e-mail: viamedica@viamedica.pl