Tom 9, Nr 4 (2024)
Obrazy w medycynie
Opublikowany online: 2024-10-07

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Eksport do Mediów Społecznościowych

Management of renal cell cancer bone metastasis — a case report on embolization and orthopaedic intervention

Dawid Sigorski12, Rafał Kidziński3, Krzysztof Pyra4, Zbigniew Żęgota5, Grzegorz Kade6
Biuletyn Polskiego Towarzystwa Onkologicznego Nowotwory 2024;9(4):321.

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Obrazy w onkologii / Pictures in oncology

Biuletyn Polskiego
Towarzystwa Onkologicznego
NOWOTWORY

2024, tom 9, nr 4, 321

© Polskie Towarzystwo Onkologiczne

ISSN: 2543–5248, e-ISSN: 2543–8077

www.nowotwory.edu.pl

Management of renal cell cancer bone metastasis — a case report on embolization and orthopaedic intervention

Dawid Sigorski 12 2Rafał Kidziński3Krzysztof Pyra4Zbigniew Żęgota5Grzegorz Kade6
1Department of Oncology and Immuno-Oncology, Clinical Hospital of the Ministry of Internal Affairs and Administration with the Warmia-Mazury Oncology Centre, Olsztyn, Poland
2Department of Oncology, University of Warmia and Mazury in Olsztyn, Poland
3Diagnostic Imaging Department, Clinical Hospital of the Ministry of Internal Affairs and Administration with the Warmia-Mazury Oncology Centre, Olsztyn, Poland
4Department of Interventional Radiology and Neuroradiology, Medical University of Lublin, Poland
5Department of Orthopedics, Traumatology and Oncology of the Musculoskeletal system, Clinical Hospital of the Ministry of Internal Affairs and Administration with the Warmia-Mazury Oncology Centre, Olsztyn, Poland
6Clinical Hospital of the Ministry of Internal Affairs and Administration with the Warmia-Mazury Oncology Centre, Olsztyn, Poland

Jak cytować / How to cite:

Sigorski D, Kidziński R, Pyra K, Żęgota Z, Kade G. Management of renal cell cancer bone metastasis a case report on embolization and orthopaedic intervention. NOWOTWORY J Oncol 2024; 74: 287.

We present the case of a 63-year-old man diagnosed with clear cell renal cell cancer (RCC) with multiple osteolytic bone metastases who was treated at our hospital. The patient underwent a pathological fracture of the left femur, surgically stabilized with a titanium plate in August of 2023. Due to the risk of spinal compression syndrome and pain, the patient underwent a palliative sacrum and Th8 radiotherapy. In October 2023, due to the destabilization of a surgical anastomosis of the femur, the patient was qualified for embolization, followed by orthopaedic surgery (Fig. 1A, B). The procedure involved puncturing the right femoral artery under local anaesthesia using the Seldinger method. A guidewire catheter was inserted on the left side. Pathological vessels supplying the richly vascularized tumour of the left thigh from the deep femoral artery were visualized. Embolization was performed using Embozene 700 μm microspheres for small pathological vessels (Fig. 1C). In the end, coils were used to close the bigger vessels. Control arteriography showed effective devascularization of the tumour (Fig. 1D). After two days, the patient underwent the removal of destabilized material from the femur with internal repositioning and stabilization with an intramedullary nail. No intraoperative complications occurred. Post-surgery, the patient was qualified for systemic therapy with ipilimumab and nivolumab as he belongs to the intermediate-risk group, according to the International Metastatic RCC Database Consortium [1].

Figure 1. Computed tomography pathological fracture and a broken stabilizing plate; A. 3D multiplanar reconstruction; B. 3D volumetric reconstruction. Digital subtraction arteriography; C. Metastatic tumour. Vascular supply from the deep femoral artery; D. Shadow of the embolization coil and effective occlusion of the tumour blood supply. Absence of flow in the distal segment of the deep femoral artery

References

  1. Wysocki PJ, Chłosta P, Chrzan R, et al. Zalecenia postępowania diagnostyczno-terapeutycznego w raku nerkowokomórkowym — aktualizacja. Onkol Prakt Klin Edu. 2022; 8(6): 424–457.