open access
Renal resistive index in hypertensive patients: a one centre study
Affiliations- Department of Internal Medicine, Faculty of Medicine, Hasanuddin University, Tamalanrea, Makassar, Indonesia
open access
Abstract
Background: Hypertension (HTN) is a leading cause of kidney dysfunction. Renal resistive index (RRI) was an
index to evaluate arterial compliance and/or resistance, reflecting the reduction of kidney function and microalbuminuria.
We investigated the relationship of RRI in hypertensive patients to detect kidney dysfunction early
detection.
Material and methods: This was a cross-sectional study at Wahidin Sudirohusodo hospital in June–November 2022. All hypertensive patients were evaluated for RRI. RRI was examined with intrarenal doppler ultrasound, and a cutoff ≥ 0.70 were used.
Results: This study included 61 subjects. Thirty-five subjects were female, and 26 subjects were male 90.2% of subjects were below 60 years. Estimated glomerular filtration rate (eGFR) level was 90.29 ± 25.19 in RRI < 0.7 and 64.91 ± 31.79 in RRI ≥ 0.7. Our study found there was a significant difference between anti-hypertensive treatment and eGFR level with the RRI group (p-value < 0.05). There was no significant difference in sex, age, proteinuria, and HTN control status in both RRI groups.
Conclusion: The renal resistive index is a useful marker for early renal dysfunction in hypertensive patients despite normal eGFR.
Abstract
Background: Hypertension (HTN) is a leading cause of kidney dysfunction. Renal resistive index (RRI) was an
index to evaluate arterial compliance and/or resistance, reflecting the reduction of kidney function and microalbuminuria.
We investigated the relationship of RRI in hypertensive patients to detect kidney dysfunction early
detection.
Material and methods: This was a cross-sectional study at Wahidin Sudirohusodo hospital in June–November 2022. All hypertensive patients were evaluated for RRI. RRI was examined with intrarenal doppler ultrasound, and a cutoff ≥ 0.70 were used.
Results: This study included 61 subjects. Thirty-five subjects were female, and 26 subjects were male 90.2% of subjects were below 60 years. Estimated glomerular filtration rate (eGFR) level was 90.29 ± 25.19 in RRI < 0.7 and 64.91 ± 31.79 in RRI ≥ 0.7. Our study found there was a significant difference between anti-hypertensive treatment and eGFR level with the RRI group (p-value < 0.05). There was no significant difference in sex, age, proteinuria, and HTN control status in both RRI groups.
Conclusion: The renal resistive index is a useful marker for early renal dysfunction in hypertensive patients despite normal eGFR.
Keywords
hypertension; renal resistive index (RRI); eGFR level; proteinuria
About this articleTitle
Renal resistive index in hypertensive patients: a one centre study
Journal
Issue
Article type
Original paper
Pages
107-112
Published online
2023-01-24
Page views
1501
Article views/downloads
290
DOI
Bibliographic record
Arterial Hypertension 2023;27(2):107-112.
Keywords
hypertension
renal resistive index (RRI)
eGFR level
proteinuria
Authors
Hasyim Kasim
Khadijah Khairunnisa Hasyim
Andi Makbul Aman
Dimas Bayu
Nur Fitriani
References (13)- Viazzi F, Leoncini G, Derchi LE, et al. Ultrasound Doppler renal resistive index: a useful tool for the management of the hypertensive patient. J Hypertens. 2014; 32(1): 149–153.
- Andrikou I, Tsioufis C, Konstantinidis D, et al. Renal resistive index in hypertensive patients. J Clin Hypertens (Greenwich). 2018; 20(12): 1739–1744.
- Giustiniano E, Pugliese L, Calabrò L, et al. Renal Resistive Index: Not Only for Kidney Clinics. J Ultrasound Med. 2022; 41(4): 1027–1030.
- Viazzi F, Leoncini G, Derchi LE, et al. Ultrasound Doppler renal resistive index: a useful tool for the management of the hypertensive patient. J Hypertens. 2014; 32(1): 149–153.
- Lubas A, Kade G, Niemczyk S. Renal resistive index as a marker of vascular damage in cardiovascular diseases. Int Urol Nephrol. 2014; 46(2): 395–402.
- Afsar B, Elsurer R. Increased renal resistive index in type 2 diabetes: Clinical relevance, mechanisms and future directions. Diabetes Metab Syndr. 2017; 11(4): 291–296.
- Gaurav K, Yalavarthy U, Chamberlain N, et al. Correlation between Renal Resistive Index and Estimated Glomerular Filtration Rate in Patients with Hypertension. J Vasc Ultrasound. 2018; 32(2): 82–84.
- Hashimoto J, Ito S. Central pulse pressure and aortic stiffness determine renal hemodynamics: pathophysiological implication for microalbuminuria in hypertension. Hypertension. 2011; 58(5): 839–846.
- Shimizu Y, Itoh T, Hougaku H, et al. Clinical usefulness of duplex ultrasonography for the assessment of renal arteriosclerosis in essential hypertensive patients. Hypertens Res. 2001; 24(1): 13–17.
- Toledo C, Thomas G, Schold JD, et al. Renal resistive index and mortality in chronic kidney disease. Hypertension. 2015; 66(2): 382–388.
- Miyoshi K, Okura T, Tanino A, et al. Usefulness of the renal resistive index to predict an increase in urinary albumin excretion in patients with essential hypertension. J Hum Hypertens. 2017; 31(1): 66–69.
- Trovato GM, Martines GF, Trovato FM, et al. Renal resistive index and parathyroid hormone relationship with renal function in nondiabetic patients. Endocr Res. 2012; 37(2): 47–58.
- Zhang F, Liu H, Liu Di, et al. Effects of RAAS Inhibitors in Patients with Kidney Disease. Curr Hypertens Rep. 2017; 19(9): 72.