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Arterial hypertension in children with type 1 diabetes
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Abstract
Arterial hypertension is a main risk factor of cardiovascular, renal and microvascular complications in diabetes. It is estimated that arterial hypertension is more prevalent among type 1 diabetic children than in general pediatric population. Arterial wall injury caused by hyperglycemia and subclinical diabetic kidney disease play a role in pathogenesis of arterial hypertension in diabetic children. Overweight and secondary insulin resistance are other factors playing role in pathogenesis of arterial hypertension. Recent guidelines recommend to perform regular blood pressure measurements and to start early antihypertensive treatment. Antihypertensive treatment in diabetic children should be based on inhibitors of converting enzyme or, in case of intolerance, blockers of angiotensin II receptor.
Abstract
Arterial hypertension is a main risk factor of cardiovascular, renal and microvascular complications in diabetes. It is estimated that arterial hypertension is more prevalent among type 1 diabetic children than in general pediatric population. Arterial wall injury caused by hyperglycemia and subclinical diabetic kidney disease play a role in pathogenesis of arterial hypertension in diabetic children. Overweight and secondary insulin resistance are other factors playing role in pathogenesis of arterial hypertension. Recent guidelines recommend to perform regular blood pressure measurements and to start early antihypertensive treatment. Antihypertensive treatment in diabetic children should be based on inhibitors of converting enzyme or, in case of intolerance, blockers of angiotensin II receptor.
Keywords
arterial hypertension, children, type 1 diabetes mellitus
About this articleTitle
Arterial hypertension in children with type 1 diabetes
Journal
Issue
Article type
Review paper
Pages
237-242
Published online
2015-03-25
Page views
819
Article views/downloads
1606
Bibliographic record
Nadciśnienie tętnicze 2014;18(4):237-242.
Keywords
arterial hypertension
children
type 1 diabetes mellitus
Authors
Małgorzata Myśliwiec
Agnieszka Szadkowska
Mieczysław Szalecki
Marta Buraczewska
Mieczysław Litwin