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Short-term prognosis of ST elevation myocardial infarction in patients with hypertension
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Abstract
Background Hypertension is an approved cardiovascular
risk factor that can modify the course of acute coronary
syndrome.
The aim of this study is to assess the inhospital course of
STEMI in hypertensive patients and to evaluate the impact
of hypertension on short-term prognosis.
Material and methods Retrospective analysis of medical
records of 1059 patients (67% men) with STEMI was performed.
The influence of coexisting hypertension on occurrence
of early complications was assessed.
Results There were 720 hypertensive patients (68%) in
group of patients with STEMI. The occurrence of selected
cardiovascular risk factors in the group of patients with
hypertension vs normotensive patients was as follows:
obesity — 15.4% vs 10% (p = 0.0365); diabetes 24% vs
16%; (p = 0.017), hypercholesterolemia 66% vs 59% (NS),
smoking 42% vs 50%, (NS). There were no statistically
significant differences in the severity of atherosclerotic lesions
in coronary arteries in both groups. Cardiogenic
shock occurred in 2.5% of patients with concomitant hypertension
and in 5% of normotensive patients (p = 0.04).
Hemorrhagic events appeared to be more frequent in
group of hypertensive patients 3.6% than in group of patients
with normal blood pressure 1.5% (p = 0.0607). Cardiovascular
mortality was higher in group of patients without
hypertension 15.6% vs 7.5%, (p = 0.0003).
Conclusions
1. Hypertensive patients have more cardiovascular risk factors
than patients with normal blood pressure.
2. Hemorrhagic events occurred more frequently in group of
patients with hypertension but without statistical significance.
3. Inhospital mortality was much higher in group of normotensive
patients with STEMI than in the group of patients
with hypertension.
Abstract
Background Hypertension is an approved cardiovascular
risk factor that can modify the course of acute coronary
syndrome.
The aim of this study is to assess the inhospital course of
STEMI in hypertensive patients and to evaluate the impact
of hypertension on short-term prognosis.
Material and methods Retrospective analysis of medical
records of 1059 patients (67% men) with STEMI was performed.
The influence of coexisting hypertension on occurrence
of early complications was assessed.
Results There were 720 hypertensive patients (68%) in
group of patients with STEMI. The occurrence of selected
cardiovascular risk factors in the group of patients with
hypertension vs normotensive patients was as follows:
obesity — 15.4% vs 10% (p = 0.0365); diabetes 24% vs
16%; (p = 0.017), hypercholesterolemia 66% vs 59% (NS),
smoking 42% vs 50%, (NS). There were no statistically
significant differences in the severity of atherosclerotic lesions
in coronary arteries in both groups. Cardiogenic
shock occurred in 2.5% of patients with concomitant hypertension
and in 5% of normotensive patients (p = 0.04).
Hemorrhagic events appeared to be more frequent in
group of hypertensive patients 3.6% than in group of patients
with normal blood pressure 1.5% (p = 0.0607). Cardiovascular
mortality was higher in group of patients without
hypertension 15.6% vs 7.5%, (p = 0.0003).
Conclusions
1. Hypertensive patients have more cardiovascular risk factors
than patients with normal blood pressure.
2. Hemorrhagic events occurred more frequently in group of
patients with hypertension but without statistical significance.
3. Inhospital mortality was much higher in group of normotensive
patients with STEMI than in the group of patients
with hypertension.
Keywords
ST elevation myocardial infarction, STEMI, J-curve, hypertension, short-term prognosis
Title
Short-term prognosis of ST elevation myocardial infarction in patients with hypertension
Journal
Issue
Article type
Original paper
Pages
134-140
Published online
2012-08-01
Page views
964
Article views/downloads
1332
Bibliographic record
Nadciśnienie tętnicze 2012;16(3):134-140.
Keywords
ST elevation myocardial infarction
STEMI
J-curve
hypertension
short-term prognosis
Authors
Paweł Salwa
Iwona Gorczyca-Michta
Beata Wożakowska-Kapłon