open access

Vol 16, No 3 (2012)
Original paper
Published online: 2012-08-01
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Short-term prognosis of ST elevation myocardial infarction in patients with hypertension

Paweł Salwa, Iwona Gorczyca-Michta, Beata Wożakowska-Kapłon
Nadciśnienie tętnicze 2012;16(3):134-140.

open access

Vol 16, No 3 (2012)
Prace oryginalne
Published online: 2012-08-01

Abstract

Background Hypertension is an approved cardiovascular
risk factor that can modify the course of acute coronary
syndrome.
The aim of this study is to assess the inhospital course of
STEMI in hypertensive patients and to evaluate the impact
of hypertension on short-term prognosis.


Material and methods Retrospective analysis of medical
records of 1059 patients (67% men) with STEMI was performed.
The influence of coexisting hypertension on occurrence
of early complications was assessed.


Results There were 720 hypertensive patients (68%) in
group of patients with STEMI. The occurrence of selected
cardiovascular risk factors in the group of patients with
hypertension vs normotensive patients was as follows:
obesity — 15.4% vs 10% (p = 0.0365); diabetes 24% vs
16%; (p = 0.017), hypercholesterolemia 66% vs 59% (NS),
smoking 42% vs 50%, (NS). There were no statistically
significant differences in the severity of atherosclerotic lesions
in coronary arteries in both groups. Cardiogenic
shock occurred in 2.5% of patients with concomitant hypertension
and in 5% of normotensive patients (p = 0.04).
Hemorrhagic events appeared to be more frequent in
group of hypertensive patients 3.6% than in group of patients
with normal blood pressure 1.5% (p = 0.0607). Cardiovascular
mortality was higher in group of patients without
hypertension 15.6% vs 7.5%, (p = 0.0003).

Conclusions
1. Hypertensive patients have more cardiovascular risk factors
than patients with normal blood pressure.
2. Hemorrhagic events occurred more frequently in group of
patients with hypertension but without statistical significance.
3. Inhospital mortality was much higher in group of normotensive
patients with STEMI than in the group of patients
with hypertension.

Abstract

Background Hypertension is an approved cardiovascular
risk factor that can modify the course of acute coronary
syndrome.
The aim of this study is to assess the inhospital course of
STEMI in hypertensive patients and to evaluate the impact
of hypertension on short-term prognosis.


Material and methods Retrospective analysis of medical
records of 1059 patients (67% men) with STEMI was performed.
The influence of coexisting hypertension on occurrence
of early complications was assessed.


Results There were 720 hypertensive patients (68%) in
group of patients with STEMI. The occurrence of selected
cardiovascular risk factors in the group of patients with
hypertension vs normotensive patients was as follows:
obesity — 15.4% vs 10% (p = 0.0365); diabetes 24% vs
16%; (p = 0.017), hypercholesterolemia 66% vs 59% (NS),
smoking 42% vs 50%, (NS). There were no statistically
significant differences in the severity of atherosclerotic lesions
in coronary arteries in both groups. Cardiogenic
shock occurred in 2.5% of patients with concomitant hypertension
and in 5% of normotensive patients (p = 0.04).
Hemorrhagic events appeared to be more frequent in
group of hypertensive patients 3.6% than in group of patients
with normal blood pressure 1.5% (p = 0.0607). Cardiovascular
mortality was higher in group of patients without
hypertension 15.6% vs 7.5%, (p = 0.0003).

Conclusions
1. Hypertensive patients have more cardiovascular risk factors
than patients with normal blood pressure.
2. Hemorrhagic events occurred more frequently in group of
patients with hypertension but without statistical significance.
3. Inhospital mortality was much higher in group of normotensive
patients with STEMI than in the group of patients
with hypertension.

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Keywords

ST elevation myocardial infarction, STEMI, J-curve, hypertension, short-term prognosis

About this article
Title

Short-term prognosis of ST elevation myocardial infarction in patients with hypertension

Journal

Arterial Hypertension

Issue

Vol 16, No 3 (2012)

Article type

Original paper

Pages

134-140

Published online

2012-08-01

Page views

964

Article views/downloads

1332

Bibliographic record

Nadciśnienie tętnicze 2012;16(3):134-140.

Keywords

ST elevation myocardial infarction
STEMI
J-curve
hypertension
short-term prognosis

Authors

Paweł Salwa
Iwona Gorczyca-Michta
Beata Wożakowska-Kapłon

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