Vol 4, No 1 (2000)
Review paper
Published online: 2000-03-09
The Role of Drug Interaction in the Hypotensive Therapy
Nadciśnienie tętnicze 2000;4(1):47-52.
Abstract
Expansion of the drug interaction knowledge base continues at a rapid rate, especially because of recent focus on the mechanisms of the cytochrome P 450 family enzymes. The failure of hipotensive pharmacotherapy may be linked with pharmacokinetic interactions of 4 main groups of antihypertensive drugs.
Keywords: cytochrome P 450 isoenzymespharmacokinetic interactionshypotensive drugs