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The Association between Ambulatory Blood Pressure and Fasting Insulin and Glucose Plasma Levels in Normotensive Premenopausal Women
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Abstract
Material and methods The study was performed in 88 premenopausal women, mean age 46 ± 4 years (22 women with normal hormone profile, 33 women with hiperandrogenism and 33 women with disturbed estrogen secretion). Mean 24 hour, day and night blood pressure and heart rate recorded by Spacelabs 90207 were analysed.
Results There was a significant correlation between fasting serum insulin level and 24-h SBP (r = 0,41, p < 0,001) and 24-h DBP (r = 0,33, p < 0,002). Fasting plasma glucose significantly correlated with 24-h SBP (r = 0,28, p < 0,01) but not with 24-h DBP. Similarly fasting insulin correlated significantly with day and night SBP (r = 0,36, p < 0,001 and r = 0,42, p < 0,001 respectively). Fasting insulin correlated significantly with day and night DBP (r = 0,28, p < 0,01 and r = 0,32, p < 0,002 respectively).
In the study group we observed significant correlation between mean night heart rate and fasting plasma glucose and insulin (r = 0,29, p < 0,005 and r = 0,37, p < 0,001 respectively).
Conclusions Our study revealed that fasting insulin level is significantly related to 24-h, day and night systolic and diastolic blood pressure in normotensive premenopausal women.
Abstract
Material and methods The study was performed in 88 premenopausal women, mean age 46 ± 4 years (22 women with normal hormone profile, 33 women with hiperandrogenism and 33 women with disturbed estrogen secretion). Mean 24 hour, day and night blood pressure and heart rate recorded by Spacelabs 90207 were analysed.
Results There was a significant correlation between fasting serum insulin level and 24-h SBP (r = 0,41, p < 0,001) and 24-h DBP (r = 0,33, p < 0,002). Fasting plasma glucose significantly correlated with 24-h SBP (r = 0,28, p < 0,01) but not with 24-h DBP. Similarly fasting insulin correlated significantly with day and night SBP (r = 0,36, p < 0,001 and r = 0,42, p < 0,001 respectively). Fasting insulin correlated significantly with day and night DBP (r = 0,28, p < 0,01 and r = 0,32, p < 0,002 respectively).
In the study group we observed significant correlation between mean night heart rate and fasting plasma glucose and insulin (r = 0,29, p < 0,005 and r = 0,37, p < 0,001 respectively).
Conclusions Our study revealed that fasting insulin level is significantly related to 24-h, day and night systolic and diastolic blood pressure in normotensive premenopausal women.
Keywords
blood pressure; hypertension; fasting insulin; fasting glucose level; hyperinsulinemia; insulin resistance; hyperandrogenism
About this articleTitle
The Association between Ambulatory Blood Pressure and Fasting Insulin and Glucose Plasma Levels in Normotensive Premenopausal Women
Journal
Issue
Article type
Original paper
Pages
35-44
Published online
2001-12-31
Page views
641
Article views/downloads
920
DOI
10.5603/ah.12847
Bibliographic record
Nadciśnienie tętnicze 2002;6(1):35-44.
Keywords
blood pressure
hypertension
fasting insulin
fasting glucose level
hyperinsulinemia
insulin resistance
hyperandrogenism
Authors
Andrzej Płoszyński
Wojciech Sobiczewski
Elżbieta Kusiak
Bartosz Curyłło
Andrzej Koprowski
Marcin Fijałkowski
Czesław Wójcikowski
Jerzy Mielnik
Andrzej Rynkiewicz