open access
The role of adipocyte products in progress of insulin resistance in obese and hypertensive patients
open access
Abstract
In the view of recent studies adipose tissue should be treated as endocrine organ producing many active substances. It is postulated that some of them (tumor necrosis factor α, leptin, adiponectin, resistin, interleukin-6) can play potential role in the mechanism leading to insulin resistance.
Better understanding of pathomechanism leading to the development of insulin resistance could contribute to improvement of therapeutic process.
Abstract
In the view of recent studies adipose tissue should be treated as endocrine organ producing many active substances. It is postulated that some of them (tumor necrosis factor α, leptin, adiponectin, resistin, interleukin-6) can play potential role in the mechanism leading to insulin resistance.
Better understanding of pathomechanism leading to the development of insulin resistance could contribute to improvement of therapeutic process.
Keywords
insulin resistance; adipose tissue; TNF-alfa; adiponectin; resistin adiponectin; leptin
Title
The role of adipocyte products in progress of insulin resistance in obese and hypertensive patients
Journal
Issue
Article type
Review paper
Pages
33-40
Published online
2004-01-23
Page views
867
Article views/downloads
1883
Bibliographic record
Nadciśnienie tętnicze 2004;8(1):33-40.
Keywords
insulin resistance
adipose tissue
TNF-alfa
adiponectin
resistin adiponectin
leptin
Authors
Monika Szulińska
Danuta Pupek-Musialik
Paweł Bogdański